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The Personnel Award program of the Heart and Stroke Foundation of Canada (HSFC) provides salary support for Canada's best young researchers. These individuals are pursuing research at universities, hospitals and institutes across Canada and abroad.
Coutts, Shelagh B. (Clinical Neurosciences, University of Calgary)
CT and MRI in the triage of TIA and minor cerebrovascular events (CATCH).
Braam, Geert Branko (Medicine, University of Alberta)
AT1 regulation in monocytes of patients with hypertension and chronic kidney disease.
Chen, Hsiao-Huei (Neuroscience, Ottawa Health Research Institute)
Mechanisms to reduce injury and improve recovery from stroke.
Choy, Jonathan C. (Molecular Biology and Biochemistry, Simon Fraser University)
Regulation of human T cell survival in heart transplant rejection.
Claydon, Victoria Elizabeth (Kinesiology, Simon Fraser University)
Cerebrovascular control following spinal cord injury.
Ezekowitz, Justin A. (Medicine, University of Alberta)
AHF-EM: Acute Heart Failure: Emergency Management.
Hess, David A. (Vascular Biology, Robarts Research Institute)
Cellular progenitors and molecular mediators of vascular regeneration.
Kirton, Adam (Pediatrics and Clinical Neurosciences, University of Calgary)
Modulation of brain plasticity after perinatal stroke.
Liu, Lixin (Pharmacology, University of Saskatchewan)
LSP1 signaling mechanisms in chemokine-induced neutrophil emigration.
Rose, Robert A. (Physiology and Biophysics, Dalhousie University)
The role of natriuretic peptide C receptor (NPR-C) in heart rate regulation.
Smith, Eric E. (Clinical Neurosciences, University of Calgary)
Cerebral small vessel disease and beta-amyloid deposition in mildly impaired cognition.
Yang, Guangdong (Kinesiology, Lakehead University)
Regulation of cystathionine gamma-lyase expression in vascular smooth muscle cells.
de Denus, Simon (Research Centre, Montreal Heart Institute)
Genetic polymorphisms related to natriuretic peptides in patients with cardiovascular disease.
Mentor: White, Michel
Rempel, Gwendolyn R. (Nursing, University of Alberta)
Explicating the influence of parenting on the development of children with CHD.
Mentor: Clark, Alexander M.
Co-Mentor: Magill-Evans, Joyce E.
Briet, Marie (Lady Davis Institute for Medical Research, Jewish General Hospital)
Remodelage des artères de petit et gros calibre dans l'insuffisance rénale chronique.
Supervisor: Schiffrin, Ernesto L.
Co-Supervisor: Lipman, Mark L.
Brodeur, Mathieu (Pharmacie, Université de Montréal)
Implication du CD36 dans la prévention de l'élastocalcinosis.
Supervisor: Moreau, Pierre
Brunt, Keith Russell (MaRS Centre, Toronto General Hospital)
Rejuvenation of human circulating progenitor cells for enhanced cell therapy in ischemic cardiomyopathy.
Supervisor: Li, Ren-Ke
de Haan, Willeke (Medical Genetics, University of British Columbia)
Interplay between lipid metabolism, beta-cell dysfunction and atherosclerosis.
Supervisor: Hayden, Michael R.
Dekker, Mark J. (Molecular Structure and Function, Hospital for Sick Children)
Hepatic overproduction of lipoprotein B-100/VLDL in insulin resistance.
Supervisor: Adeli, Khosrow
Fish, Jason E. (Cardiovascular Disease, Gladstone Institute)
MicroRNA regulation of vascular function.
Supervisor: Srivastava, Deepak
Jantzie, Lauren L. (Neurology, Children's Hospital, Boston)
Glutamate receptor anatagonism and neonatal hypoxia-ischemia.
Supervisor: Jensen, Frances E.
Johnson, Rosalyn P. (Medicine, Brigham and Women's Hospital)
Regulation of AMPK and its substrates in endothelial cells during oxidative stress.
Supervisor: Michel, Thomas
Khajoee, Vahid (MaRS Centre, Hospital for Sick Children)
The role of inositol 1,4,5-triphosphate kinase C in pathogenesis of Kawasaki disease.
Supervisor: Yeung, Rae S. M.
Khan, Aarlenne (Centre for Neuroscience Studies, Queen's University)
The role of attention in visually-guided movements.
Supervisor: Munoz, Douglas P.
Co-Supervisor: Flanagan, John R.
Kienesberger, Petra C. (Pediatrics, University of Alberta)
The role of adipose triglyceride lipase in cardiac energy metabolism.
Supervisor: Dyck, Jason R. B.
Kim, Paul Y. (Medicine, Henderson Research Centre)
Impact of ɣ' - fibrinogen on clot formation at sites of plaque rupture.
Supervisor: Weitz, Jeffrey I.
Lessard, Sarah J. (Metabolism Section, Joslin Diabetes Centre)
Investigating the role of SNARK as a regulator of cardiac glucose metabolism.
Supervisor: Goodyear, Laurie J.
MacLellan, Crystal L. (Neurology, University of California at Los Angeles)
Manipulating brain plasticity to improve functional recovery after stroke.
Supervisor: Carmichael, Stanley T.
Marchant, David (iCAPTURE Centre, St. Paul's Hospital)
Matrixmetalloproteinases during coxsackievirus induced myocarditis.
Supervisor: McManus, Bruce M.
Michael, Georghia (Research Centre, Montreal Heart Institute)
Calcium handling abnormalities and the induction of atrial fibrillation in heart failure.
Supervisor: Nattel, Stanley
Co-supervisor: Comtois, Philippe
Montezano, Augusto C. I. (Kidney Research Centre, Ottawa Health Research Institute)
NOX homologues and redox signaling in hypertension.
Supervisor: Touyz, Rhian M.
Nair, Krishnakumar (Cardiology, University Health Network)
Transmural activation in human ventricular fibrillation.
Supervisor: Nanthakumar, Kumaraswamy
Pamenter, Matthew E. M. (Pediatrics, University of California at San Diego)
Innate immunity and reactive oxygen species contribute to neurogeneration following ischemic stroke.
Supervisor: Haddad, Gabriel
Pless, Stephan (Anesthesiology, Pharmacology and Therapeutics, University of British Columbia)
Investigating anti-arrhythmic inhibition of voltage-gated sodium channels with unnatural amino acids and fluorescence spectroscopy.
Supervisor: Ahern, Christopher A.
Poburko, Damon T. (Molecular and Cellular Physiology, Stanford University)
Voltage-gated calcium channels compete for "slots" on presynaptic membranes: Molecular determinants and functional consequences.
Supervisor: Tsien, Richard W.
Rayner, Katey (Lipid Metabolism Unit, Massachusetts General Hospital)
Identifying novel mechanisms of CD36 activation in atherosclerosis and Alzheimer's disease.
Supervisor: Moore, Kathryn J.
Schussler, Olivier (Cardiac Surgery, University of Ottawa Heart Institute)
Cardiac tissue regeneration using progenitor/stem cells seeded in a new biofunctionalized injectable collagen matrix.
Supervisor: Ruel, Marc
Singh, Anamika (Michael Smith Laboratories, University of British Columbia)
Functional effects of omega-3 fatty acids on T-type calcium channel splice variants expressed under normal and cardiopathic conditions.
Supervisor: Snutch, Terrance P.
Su, Qiaozhu (Clincial Biochemistry, Hospital for Sick Children)
Characterization of the molecular links between apolipoprotein B100 mRNA translation and hepatic insulin resistance.
Supervisor: Adeli, Khosrow
Tamplin, Owen (Hematology-Oncology, Children's Hospital, Boston)
Homing and engrafment of hematopoietic stem cells in the zebrafish embryo.
Supervisor: Zon, Leonard
Voskas, Daniel (Samuel Lunenfeld Research Institute, Mount Sinai Hospital)
Roles for Gsk-3 in cardiovascular development.
Supervisor: Woodgett, James R.
Woo, Wai Hong Connie (Medicine, Columbia University)
Role of innate immunity in stress-induced apoptosis and plaque progression in atherosclerosis.
Supervisor: Tabas, Ira
Xi, Liang (Medicine and Physiology, Toronto General Hospital)
The effect of human C-reactive protein on insulin sensitivity and the underlying mechanisms.
Supervisor: Lewis, Gary F.
Yogi, Alvaro (Kidney Research Centre, Ottawa Health Research Institute)
Magnesium regulation of vascular function in hypertension: role of TRPM7.
Supervisor: Touyz, Rhian M.
Audet, Martin (Biochimie, Université de Montréal)
Beta-blockers: exploring the structural determinant for ligand-biased signalling.
Supervisor: Bouvier, Michel
Bowden, Kristin (iCapture Centre, University of British Columbia)
Cholesteryl ester storage disease as a model for understanding intracellular cholesterol homeostasis and HDL biogenesis.
Supervisor: Francis, Gordon A.
Declercq, Vanessa (Physiology, University of Manitoba)
Conjugated linoleic isomers regulate blood pressure through modulation of adipose tissue function.
Supervisor: Zahradka, Peter
Co-Supervisor: Taylor, Carla G.
Detombe, Sarah A. (Imaging Research Laboratory, Robarts Research Institute)
Direct comparison of retrospectively gated cardiac micro-CT and conductance catheter measurements in mice.
Supervisor: Drangova, Maria
Dragert, Katie (Rehabilitation Neuroscience Laboratory, University of Victoria)
Efficacy of phased resistance training to stabilize ankle muscle strength after stroke.
Supervisor: Zehr, E. Paul
Feric, Nicole (Biochemistry, Queen's University)
Interaction of lipoprotein (a) with the plasminogen system: mechanisms and pathophysiological consequences.
Supervisor: Koschinsky, Marlys L.
Foley, Jonathan H. (Biochemistry, Queen's University)
The role of TAFIa in regulating fibrinolysis.
Supervisor: Nesheim, Michael E.
Gamble, John-Michael (Public Health Sciences, University of Alberta)
Impact of insulin therapy on cardiovascular morbidity and mortality in patients with type 2 diabetes.
Supervisor: Eurich, Dean T.
Co-Supervisor: Johnson, Jeffrey A.
Leung, Wan Yee Yvonne (Kinesiology and Health Science, York University)
Degree, correlates and outcomes of posttraumatic growth among cardiac patients.
Supervisor: Grace, Sherry L.
Ley, Sylvia H. (Nutritional Sciences, University of Toronto)
The impact of maternal metabolic abnormalities on breastmilk and infant metabolic development.
Supervisor: Hanley, Anthony J. G.
McVea, David (Psychiatry, University of British Columbia)
Testing the role of muscle spindles in cortical plasticity following stroke.
Supervisor: Murphy, Timothy H.
Oreopoulos, Antigone (School of Public Health, University of Alberta)
The obesity paradox in hearth failure: a pilot study.
Supervisor: Norris, Colleen M.
Ouimet, Mirielle I. (Lipoprotein and Atherosclerosis Research Group, University of Ottawa Heart Institute)
Regulation of lipid droplet-associated cholesterol efflux in macrophage foam cells.
Supervisor: Marcel, Yves L.
Parsons, Matthew (Medicine, Memorial University of Newfoundland)
KATP channel regulation of orexin neurons.
Supervisor: Hirasawa, Michiru
Piskuric, Nikol A. (Biology, McMaster University)
Functional and anatomical characterization of rat aortic bodies.
Supervisor: Nurse, Colin A.
Seliske, Laura M. (Community Health and Epidemiology, Queen's University)
Influence of the built environment on physical activity and obesity in Canadian youth.
Supervisor: Janssen, Ian M.
Co-supervisor: Pickett, William
Thackeray, James (Cardiac PET Centre, University of Ottawa Heart Institute)
Impact of glycaemic therapy in progression and regression of diabetic heart disease.
Supervisor: DaSilva, Jean N.
Co-supervisor: Beanlands, Robert S.
Thorn, Stephanie (Cellular and Molecular Medicine, University of Ottawa Heart Institute)
Pathophysiological mechanism of the human Arg302GIn-PRKAG2 mutation-induced metabolic cardiomyopathy.
Supervisor: DaSilva, Jean N.
Co-supervisor: Gollob, Michael
Torbey, Sami (School of Computing, Queen's University)
Risk stratification for sudden cardiac death through analysis of the paced QRS complex.
Supervisor: Akl, Selim G.
Co-supervisor: Redfearn, Damian
Wong, Emily Yee-Wah (Medical Biophysics and Surgery, University of Western Ontario)
Patient assessment of carotid plaque ulceration using Doppler ultrasound waveform analysis.
Supervisor: Holdsworth, David W.
Co-supervisor: Poepping, Tamie L.
Wong, Tse Yuan (Jerry) (iCapture Centre, St. Paul's Hospital)
The role of serum response factor in viral myocarditis.
Supervisor: Luo, Honglin
Co-supervisor: McManus, Bruce
Zhang, Yan (Cardiac Surgery, University of Ottawa Heart Institute)
PET imaging for the assessment of transplanted progenitor cells delivered in biomatrices.
Supervisor: Suuronen, Erik J.
Co-supervisor: Ruel, Marc
Zhao, Ruogang (Mechanical and Industrial Engineering, University of Toronto)
Biomechanical regulation of apoptosis in aortic valve interstitial cells.
Supervisor: Simmons, Craig A.