HSFC Personnel Awards Program - 2004/2005

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Personnel awards funded by HSFC for 2004/2005:

Visiting Scientists

  • Karsan, Aly (Medical Biophysics, British Columbia Cancer Research Centre)
    Sponsor: Veenstra, Tim (Laboratory of Proteomics and Analytical Technologies, NCI - Frederick Cancer Research Facility)
    Proteomatic approaches to endothelial cell signaling.

New Investigator

* Applicants funded via the HSFC/CIHR Health Research Partnership Fund.

  • *Blostein, Mark D. (Medicine, McGill University)
    HSFC/CIHR Health Research Partnership Fund
    Novel role of gamma-carboxyglutamic acid in vascular biology.
  • Brown, Arthur (Neurodegeneration Research Group, Robarts Research Institute)
    Genetic control of heart development and autonomic dysreflexia.
  • Childs, Sarah J. (Biochemistry and Molecular Biology, University of Calgary)
    Blood vessel development in zebrafish.
  • Coorssen, Jens R. (Physiology & Biophysics, University of Calgary)
    Defining the fusion site of regulated exocytosis.
  • Czubryt, Michael P. (Physiology, University of Manitoba)
    McDonald Scholarship Award

    Roles of MEF2 and HDAC5 in cardiac failure and hypertrophy.
  • Dawson, John F (Chemistry and Biochemistry, University of Guelph)
    Characterization of human cardiac actin mutations linked to hypertrophic and dilated cardiomyopathies.
  • Drolet, Benoit (Centre de recherche, Université Laval)
    The modulating effects of diabetes, obesity and genetics on the electrophysiology of QT-prolonging drugs.
  • Fernandez-Patron, Carlos A. (Biochemistry, University of Alberta)
    New vasoconstrictor mechanism triggered by transactivation of a growth pathway.
  • Frayne, Richard (Radiology, University of Calgary)
    Endovascular MR system for stroke therapy.
  • Hebert, Terence (Research Centre, Université de Montréal)
    Organization and specificity in G protein-coupled receptor signalling.
  • *Hill, Michael D (Clinical Neurosciences, University of Calgary)
    HSFC/CIHR Health Research Partnership Fund
    Stratifying risk in acute ischemic stroke.
  • Jacques, Danielle (Anatomy and Cell Biology, Université de Sherbrooke)
    Regulation of intracellular calcium by NPY in endocardial endothelial cells.
  • Kong, Jiming (Human Anatomy and Cell Science, University of Manitoba)
    Focus on Stroke

    BNIP3-activated atypical apoptosis pathway in ischemic neuronal cell death.
  • Liaw, Patricia C.Y. (Medicine, McMaster University)
    Modulation of inflammation and apoptosis by activated protein C, a natural anticoagulant.
  • Liu, Fang (Neuroscience, Centre for Addiction and Mental Health)
    Focus on Stroke

    Protein-protein interactions in the regulation of AMPA receptor mediated neurotoxicity.
  • MacDonald, Justin A. (Biochemistry and Molecular Biology, University of Calgary)
    Characterization of CHASM involvement in cGMP-evoked calcium desensitization in vascular smooth muscle.
  • Melo, Luis G (Physiology, Queen's University)
    Gene therapy for long term myocardial protection and rescue.
  • Mesaeli, Nasrin (Stroke and Vascular Disease, University of Manitoba)
    Role of endoplasmic reticulum in vascular development.
  • Netticadan, Thomas (Physiology, University of Manitoba)
    Target Obesity

    Mechanisms underlying contractile dysfunction in type II diabetes.
  • Pasumarthi, Kishore Babu S (Pharmacology, Dalhousie University)
    Isolation and characterization of cardiac progenitor cells.
  • Reid, Robert D. (Prevention and Rehabilitation Centre, University of Ottawa)
    Interventions to promote physical activity for the secondary prevention of CAD.
  • Richard, Darren E. (Medicine, Université Laval)Z
    Vasoactive hormones and hypoxia in the control of vascular endothelial growth factor.
  • Rodger, Marc A. (Medicine, University of Ottawa)
    Thrombophilia: novel associations and therapeutic interventions.Z
  • Thorin, Eric (Surgery, University of Montreal)
    Influence des changements de couplages récepteurs / protéines G sur la fonction endothéliale.
  • Todd, Kathryn G. (Psychiatry, University of Alberta)
    Barnett Research Award
    Focus on Stroke

    Investigations of novel strategies to improve cellular and behavioral outcomes after adult and perinatal cerebral ischemia.
  • Trigatti, Bernardo L (Biochemistry, McMaster University)
    Effect of tissue specific expression or suppression of the HDL receptor SR-BI on cardiovascular disease.
  • Tsushima, Robert G (Medicine, University of Toronto)
    Defining the fusion site of regulated exocytosis. Regulation of cardiac calcium-activated nonselective cation channels.
  • Wang, Hui Di (Pharmacology, Brock University)
    Vascular gp-91phox containing NADPH oxidase in angiotensin II-induced hypertension.
  • Welsh, Donald G. (Physiology and Biophysics, University of Calgary)
    Basis of pyrimidine-induced vasoconstriction.
  • Werstuck, Geoffrey H. (Biochemistry, McMaster University)
    Mechanisms by which diabetes mellitus promotes the development and progression of atherosclerosis.
  • Whelan, Patrick J. (Medical Physiology, University of Calgary)
    Focus on Stroke

    Sensory control of locomotion in the developing mouse.
  • Whitman, Stewart C. (Pathology and Laboratory Medicine, University of Ottawa Heart Institute)
    The role of the immune system in atherosclerosis: mechanism of action of IL-12 and IL-18.
  • Wilson, Richard J.A. (Medical Physiology & Biophysics, University of Calgary)
    Focus on Stroke

    Chemoreceptor interactions and neural plasticity in the control of breathing.
  • Zha, Xiaohui (Hormone, Growth and Development, Ottawa Hospital Research Institute)
    ABCA1 and molecular mechanism of cholesterol efflux.
  • Zhang, Shetuan (Physiology, St. Boniface General Hospital Research Centre)
    The mechanisms of sudden cardiac death caused by cocaine.
  • Zheng, Xi-Long (Biochemistry and Molecular Biology, University of Calgary)
    Atherogenesis: an investigation of vascular smooth muscle phospholipase D.

Research Fellowship

  • *Aarts, Michelle M. (Cellular & Molecular Neuroscience, Toronto Western Research Institute)
    HSFC/CIHR Health Research Partnership Fund
    Treatment of ischemic injury and excitotoxicity by uncoupling NMDA receptor - PSD95 interactions.
    Supervisor: Tymianski, Michael 
  • Ainslie, Philip N. (Physiology and Biophysics, University of Calgary)
    Focus on Stroke

    Ventilatory and cerebrovascular control in healthy humans with obstructive sleep apnea.
    Supervisor: Poulin, Marc J. 
  • Allister, Emma M. (Vascular Biology Research Group, Robarts Research Institute)
    Regulation of lipoprotein secretion from cultured primary hepatocytes.
    Supervisor: Huff, Murray W. 
  • Altier, Christophe (Physiology & Biophysics, University of Calgary)
    Determinants of N-type calcium channel targeting and physiology.
    Supervisor: Zamponi, Gerald W. 
  • Andelfinger, Gregor (Lab of Cardiac Growth and Differentiation, IRCM)
    Genetic dissection of heart development.
    Supervisor: Nemer, Mona 
  • Argmann, Carmen A. (Centre National de Recherche en Santé, Institut de Génétique et de Biologie Moléculaire et Cellulai)
    The phenotypic and molecular consequences of signaling through hepatic LRH-1 in mice.
    Supervisor: Auwerx, Johan 
  • Arrell, David Kent (Cardiovascular Research Laboratory, Mayo Clinic)
    Proteomics of cardiac stress.
    Supervisor: Terzic, Andre 
  • Bateman, Ryon M. (UBC McDonald Research Labs, St. Paul's Hospital)
    Mechanism of myocardial dysfunction in sepsis.
    Supervisor: Walley, Keith R 
  • Beletsky, Vadim Y.U. (Clinical Neurological Sciences, Robarts Research Institute)
    Doppler or angiography prior to carotid surgery.
    Supervisor: Spence, J. David 
  • Borman, Meredith A. (Biochemistry & Molecular Biology, University of Calgary)
    Exploring a novel mechanism of cGMP-phosphodiesterase regulation in smooth muscle.
    Supervisor: Walsh, Michael P 
  • Borradaile, Nica M. (Department of Internal Medicine, Washington University)
    Cardiac mechanisms of lipotoxicity.
    Supervisor: Schaffer, Jean E. 
  • Cayabyab, Francisco S. (Psychiatry, University of British Columbia)
    Focus on Stroke

    Gap junctional hemichannels in astrocytes: regulation in normal and injured CNS.
    Supervisor: MacVicar, Brian A. 
  • Champagne, Maud C.M. (Medicine, Institut Universitaire de Gériatrie de Montréal)
    Focus on Stroke

    États mentaux et troubles de la communication chez les cérébrolésés droits.
    Supervisor: Joanette, Yves 
  • Chung, Ada W.Y. (The iCAPTURE Centre, St. Paul's Hospital)
    HSFC/AstraZeneca Canada Fellowship

    Vasomotor dysfunction and signalling in human diabetes.
    Supervisor: van Breemen, Cornelis 
  • Clark, Stephen (Physiology & Biophysics, University of Calgary)
    Therapeutic nitric oxide inhalation in inflammatory disease - formation/function of S-nitroso-molecules.
    Supervisor: Kubes, Paul 
  • Claydon, Thomas W. (Physiology, University of British Columbia)
    Focus on Stroke

    Molecular mechanism underlying the ischemia and pH-sensitivity of the neuronal and smooth muscle voltage-gated K+channels, Kv1.4 and Kv1.5.
    Supervisor: Fedida, David 
  • Coutts, Shelagh B. (Clinical Neurosciences, Foothills Hospital)
    Vascular imaging of acute stroke for identifying occlusion and nominal perfusion (vision).
    Supervisor: Buchan, Alastair M. 
  • Di Legge, Silvia (Clinical Neurological Sciences, London Health Sciences Centre)
    Impact of lesion side on acute stroke treatment.
    Supervisor: Hachinski, Vladimir 
  • Emsley, Jason George (Neurology & Neurosurgery, Massachusetts General Hospital)
    Molecular phenotyping of newborn cortical neurons recruited from endogenous neural precursors.
    Supervisor: Macklis, Jeffrey 
  • Fry, W. Mark (Physiology, Queen's University)
    Target Obesity

    Electrophysiological characterisation of orexinergic neurons in the lateral hypothalamus.
    Supervisor: Ferguson, Alastair 
  • Fuse, Koichi (Heart & Stroke/Richard Lewar Centre of Excellence, Toronto General Hospital)
    Roles of innate immune signaling pathways including Toll-like receptors in viral heart failure.
    Supervisor: Liu, Peter 
  • Gilbert, Robert W. (Pharmacology, Dalhousie University)
    Focus on Stroke

    Stroke, gene expression and neuroprotection: targets for treatment.
    Supervisor: Robertson, Harold 
  • Gong, Nanling (Richard Lewar Cardiovascular Centre, University of Toronto)
    Regulation of Kv4 potassium channels in cardiac hypertrophy and heart disease.
    Supervisor: Backx, Peter H. 
  • Gould, Douglas B. (The Jackson Laboratory, Howard Hughes Medical Institute)
    Focus on Stroke

    Identification and characterization of a model for perinatal and age-related stroke.
    Supervisor: John, Simon M.W. 
  • Gramolini, Anthony (Banting and Best Department of Medical Research, University of Toronto)
    Physiological consequences of calcium dysregulation in cardiac muscle.
    Supervisor: MacLennan, David H. 
  • Gui, Yu (Biochemistry & Molecular Biology, University of Calgary)
    Effects of the estrogen metabolite, 2-methoxyestradiol, on vascular smooth muscle.
    Supervisor: Zheng, Xi-Long 
  • Haidar, Bassam (Lipoprotein and Atherosclerosis Research Group, University of Ottawa Heart Institute)
    HSFC/Pfizer Canada Fellowship

    Control of hepatic lipidation and secretion of apolipoprotein A-I.
    Supervisor: Marcel, Yves L 
  • Healey, Jeffrey S. (Department of Cardiology, McMaster University)
    HSFC/AstraZeneca Canada Fellowship

    Angiotensin receptor blockade to reverse atrial remodelling in patients with atrial fibrillation.
    Supervisor: Connolly, Stuart J 
  • Huang, Yuan (Physiology, University of Saskatchewan)
    Focus on Stroke

    Brain HO/CO system, vascular dementia and hypertension.
    Supervisor: Wang, Rui 
  • Jasmin, Jean-Francois (Molecular Pharmacology, Albert Einstein College of Medicine)
    Roles of caveolins in pulmonary hypertension and structural remodeling of the lungs.
    Supervisor: Lisanti, Michael P. 
  • Jassal, Davinder S. (Cardiology, Massachusetts General Hospital)
    The role of nitric oxide synthase 3 in ventricular remodeling.
    Supervisor: Scherrer-Crosbie, Marielle 
  • Jin, Ya-Ping (Clinical Neurological Sciences, London Health Sciences Centre)
    4th ICPC/HSFC/CCS Fellowship in Preventive Cardiology

    Additional couseling support for vascular risk factors control: preventing stroke and dementia.
    Supervisor: Hachinski, Vladimir 
  • Kassiri, Zamaneh (Experimental Therapeutics, Princess Margaret Hospital)
    Role of TIMMP-3 in development and progression of experimental heart disease.
    Supervisor: Khokha, Rama 
  • Kennedy, James (Clinical Neurosciences, University of Calgary)
    Focus on Stroke

    Patient preferences for outcome with thrombolysis following acute ischemic stroke.
    Supervisor: Buchan, Alastair M. 
  • Kerfant, Benoit-Gilles (Physiology and Medicine, University of Toronto)
    The role of Pi3Kgamma in control and failing heart function.
    Supervisor: Backx, Peter H. 
  • Kiss, Enikö (Biochemistry and Molecular Biology, University of Calgary)
    The molecular basis of calcium sensitization of vascular smooth muscle contraction.
    Supervisor: Walsh, Michael P. 
  • Ko, Dennis T. (Cardiology, Institute for Clinical Evaluative Sciences)
    Quality care of diabetic patients admitted with acute myocardial infarction.
    Supervisor: Tu, Jack V 
  • Koeberle, Paulo (Cellular and Molecular Biology, Toronto Western Hospital)
    Potassium channel blockade in microglia: A potential therapeutic treatment in mammalian models of stroke.
    Supervisor: Schlichter, Lyanne C. 
  • Lagneux, Caroline (Immunology, Montreal General Hospital)
    Focus on Stroke

    The genetic dissection of stroke in the mouse model.
    Supervisor: Skamene, Emil 
  • Lee, Paul C. (Cardiology, Toronto General Hospital)
    Microvascular dysfunction as etiology and target for therapy in heart failure.
    Supervisor: Liu, Peter 
  • Lekas, Michael C. (Division of Cardiology, St. Michael's Hospital)
    Interactions between angiopoietin-1 and angiopoietin-2 in neovascularization of the ischemic hindlimb.
    Supervisor: Stewart, Duncan J. 
  • Lessard, Andree A.L. (Neurobiology, Cornell University)
    Subcellular localization of neurokinin receptors in the substantia nigra: relationship with hypertension.
    Supervisor: Pickel, Virginia Margaret 
  • Li, Jia (Cardiology, Hospital for Sick Children)
    Oxygen consumption during cardiopulmonary bypass in children.
    Supervisor: Redington, Andrew N. 
  • Martino, Tami A. (Physiology, University of Toronto)
    Molecular circadian regulation of heart disease.
    Supervisor: Backx, Peter H. 
  • McCarter, Sarah Denise (Cardiology, St. Michael's Hospital)
    HSFC/ Pfizer Canada Fellowship

    Vascular protective gene therapy to treat the acute respiratory distress syndrome.
    Supervisor: Stewart, Duncan J. 
  • McGavock, Jonathan (Internal Medicine, University of Texas Southwestern Medical Center)
    The impact of myocardial lipid accumulation on cardiac function in obese insulin resistant humans.
    Supervisor: Victor, Ronald 
  • Morrison, Janna (Physiology, University of Adelaide)
    Restriction of fetal growth during pregnancy and programming of hypertension in adulthood.
    Supervisor: McMillen, I. Caroline 
  • Morrison, Katherine M (Medicine, McMaster University)
    Atherosclerosis birth cohort: The ABC study.
    Supervisor: Yusuf, Salim 
  • Naska, Sibel (Research Institute, Hospital for Sick Children)
    Focus on Stroke

    Role of the p53 family in excitotoxicity-induced neuronal apoptosis.
    Supervisor: Miller, Freda D 
  • Ndisang, Joseph Fomusi (Physiology, University of Saskatchewan)
    The cardio-protective and anti-inflammatory circuits of hydrogen sulphide.
    Supervisor: Wang, Rui 
  • Nian, Min (Heart & Stroke/Richard Lewar Centre of Excellence, Toronto General Hospital)
    Molecular pathogenesis of viral myocarditis.
    Supervisor: Liu, Peter 
  • O'Donnell, Martin (Medicine, Hamilton Civic Hospital Research Centre)
    Focus on Stroke

    Improving anticoagulant control in patients with erratic control by daily vitamin K supplementation. 2. Effect of antithrombotic therapy and cerebrovascular risk factors on cognitive decline.
    Supervisor: Hirsh, Jack 
  • Palmer, Daniel (Cardiovascular Research Institute, University of California)
    G12/13 signalling in cardiovascular biology.
    Supervisor: Coughlin, Shaun R. 
  • Pang, Li (Brain Research Centre, University of British Columbia)
    Prophylactic gene therapy for stroke.
    Supervisor: Cynader, Max S 
  • Rezvani, Mojgan (Medicine, Harvard Medical School)
    Genomics analysis of mouse embryonic stem cells derived cardiac myocytes.
    Supervisor: Dzau, Victor J. 
  • Rocnik, Edward F. (Molecular Cardiology, Boston University)
    Regulation of vascular smooth muscle cell hypertrophy and vascular remodeling by Akt.
    Supervisor: Walsh, Kenneth 
  • Rosenbaum, Shayna (Geriatrics, Baycrest Centre for Geriatric Care)
    Focus on Stroke

    Integration of affective and cognitive processing within the frontal lobes in stroke.
    Supervisor: Stuss, Donald T. 
  • Ruest, Louis-Bruno (Molecular, Cellular and Cranialfacial Biology, University of Louisville)
    Endothelian-A receptor signalling during cardiac neural crest cell development.
    Supervisor: Clouthier, David E. 
  • Sader, Sawsan (Medicine & Physiology, The Toronto Hospital)
    The role of gelsolin in cardiac remodeling and failure.
    Supervisor: Liu, Peter 
  • Saposnik, Gustavo (Neurological Sciences, London Health Sciences Centre)
    Focus on Stroke

    Preserving cognition by improving vascular risk factors control: a randomized controlled trial.
    Supervisor: Hachinski, Vladimir 
  • Semeniuk, Lisa M. (Medicine, University of Calgary)
    Cardiac resynchronization therapy - Evaluating predictors of response.
    Supervisor: Exner, Derek V. 
  • Smith, Lori K. (Canadian Centre for Behavioural Neuroscience, University of Lethbridge)
    Effects of stress and glucocorticoids on recovery after stroke.
    Supervisor: Metz, Gerlinde A. 
  • Spears, Julian (Neurosurgery, Toronto Western Hospital)
    Development of a prediction model for neurological outcome following surgery of brain AVMs in the prevention of hemorrhagic stroke.
    Supervisor: Wallace, M. Christopher 
  • Steinberg, Gregory R. (St. Vincent's Institute of Medical Research)
    Target Obesity

    Intracellular mechanisms contributing to skeletal muscle leptin resistance in obesity.
    Supervisor: Kemp, Bruce E 
  • Tanaka, Ryota (Cell Biology & Anatomy, University of Calgary)
    Focus on Stroke

    Prolactin stimulation of cortical regeneration after stroke.
    Supervisor: Weiss, Samuel 
  • Tannenbaum, Beth M. (Neurology and Neurosurgery, Montreal Neurological Institute)
    Target Obesity

    Alterations of brain circuitry in obesity: The role of reward and motivational state.
    Supervisor: Dagher, Alain 
  • Touret, Nicolas (Department of Cell Biology, Hospital for Sick Children)
    HSFC/AstraZeneca Canada Fellowship

    Role of the scavenger receptor CD36 in the initiation of inflammatory responses involved in atherosclerosis.
    Supervisor: Grinstein, Sergio 
  • Trivieri, Maria Giovanna (Physiology, University of Toronto)
    Role of thyroid hormone in heart.
    Supervisor: Backx, Peter H. 
  • Tsuji, Yukiomi (Research, Montreal Heart Institute)
    Potassium channel modifications in rabbits with acquired QT prolongation and torsades de pointes.
    Supervisor: Nattel, Stanley 
  • Ustinova, Ksenia Iv (Institut de réadaptation de Montréal, Université de Montréal)
    Focus on Stroke

    The control of posture and bilateral limb movements in stroke patients.
    Supervisor: Levin, Mindy F. 
  • Uwabo, Jiro (Medicine, University of Montreal)
    Molecular genetics of hypertension.
    Supervisor: Hamet, Pavel 
  • Vanderluit, Jacqueline Liza (Neuroscience Research Group, University of Ottawa)
    P107 and pRb in stem cell proliferation and neurogenesis following stroke.
    Supervisor: Slack, Ruth S. 
  • Verma, Atul (Cardiology, The Cleveland Clinic Foundation)
    The radiofrequency ablation of atrial fibrillation trial (RAAFT).
    Supervisor: Natale, Andrea 
  • Wan, Xiang (Brain and Behaviour & Cell Biology, Hospital for Sick Children)
    Attenuation of excitotoxicity using novel Src kinase inhibitors.
    Supervisor: Salter, Michael W. 
  • Wang, Hao (Cardiac Growth, IRCM)
    Molecular dissection of angiotensin II-dependent cardiac hypertrophy.
    Supervisor: Nemer, Mona 
  • Weerapura, Manjula (Physiology, University of Toronto)
    Focus on Stroke

    Regulation of NMDA channels by protein kinase A-dependent signaling pathways.
    Supervisor: MacDonald, John F. 
  • Wei, Wen-Li (Department of Physiology, University of Toronto)
    Regulation of TRPM-like current in cerebral stroke.
    Supervisor: MacDonald, John F 
  • Wong, Wei (Vollum Institute, Oregon Health & Science University)
    Functional analysis of mAKAP signaling complexes in cardiomyocytes.
    Supervisor: Scott, John D. 
  • Yoshida, Hideyuki (Genes & Development Research Group, University of Calgary)
    Focus on Stroke

    Adult neural stem cells to treat stroke.
    Supervisor: Weiss, Samuel 
  • Yoshioka, Mayumi (Anatomy and Physiology, Centre hospitalier de l'Université Laval)
    Target Obesity

    Identification and cloning of appetite and satiety controlling genes.
    Supervisor: St-Amand, Jonny 
  • Zaid, Ahmed Elagili (Biochemical Neuroendocrinology, IRCM)
    Focus on Stroke

    NARC-1 and familial hypercholestrolemia type 3.
    Supervisor: Seidah, Nabil G. 
  • Zhu, Dong Ya (Physiology & Biophysics, University of Calgary)
    Focus on Stroke

    Nitric oxide-mediated down-regulation of GABAa receptor function following cerebral ischemia.
    Supervisor: Lu, YouMing 
  • Zou, Renqiang (Research Center, Montreal Heart Institute)
    Mechanisms of AF maintenance and termination probed with a realistic mathematical model.
    Supervisor: Nattel, Stanley

Doctoral Research Award

* - Applicants funded via the HSFC/CIHR Health Reseach Partnership Fund. 

  • Ander, Bradley P. (Physiology, St. Boniface General Hospital Research Centre)
    Antiarrhythmic effects of dietary flax seed in ischemia/reperfusion.
    Supervisor: Pierce, Grant N. 
  • Anderson, Kristal D. (Kinesiology, University of Saskatchewan)
    Target Obesity

    Target Obesity: Identifying childhood predictors of adulthood obesity.
    Supervisor: Chad, Karen E. 
  • Ardern, Chris (Kinesiology & Health Education, Queen's University)
    Obesity screening, future health risk, and the role of gender.
    Supervisor: Katzmarzyk, Peter T. 
  • Atkins, Ross (Biology & Biochemistry, University of Victoria)
    Integrin function in the migration of cardiac neural crest cells.
    Supervisor: Burke, Robert D. 
  • Balasubramaniam, Janani (Pathology, University of Manitoba)
    Focus on Stroke

    Time and age dependent responses following intracerebral hemorrhage in rodent brain.
    Supervisor: Del Bigio, Marc R. 
  • Bandali, Karim S. (Physiology, University of Toronto)
    The effects of hyperoxia on the neonatal heart and its mechanism.
    Supervisor: Wittnich, Carin 
  • Bernier, Virginie (Médecine, Hôpital du Sacré-Coeur)
    Des chaperons pharmacologiques pour traiter le diabète insipide néphrogénique.
    Supervisor: Bichet, Daniel G. 
  • Bhagat, Yusuf A. (Biomedical Engineering, University of Alberta)
    Focus on Stroke

    Diffusion tensor magnetic resonance imaging of clinical stroke.
    Supervisor: Beaulieu, Christian
  • Blackburn, Patricia (Centre de recherche, Hôpital Laval)
    Target Obesity

    Taille des particules LDL et HDL: différences sexuelle et raciales et impact de l'entraînement en endurance.
    Supervisor: Després, Jean-Pierre 
  • Cardin, Sophie (Centre de recherche, Institut de cardiologie de Montréal)
    Changement de l'expression génique au cours du remodelage auriculaire et ventriculaire induit par l'insuffisance cardiaque.
    Supervisor: Nattel, Stanley 
  • Chen, Tim T. (Pharmacology and Therapeutics, University of Calgary)
    Vascular smooth muscle delayed rectifier K+ channel regulation of resistance arterial diameter.
    Supervisor: Cole, William C. 
  • Choi, Hong Y. (Medicine, University of Alberta)
    Apolipoprotein-mediated lipid efflux from arterial smooth muscle cells.
    Supervisor: Francis, Gordon A. 
  • Choi, Hyun Beom (Pharmacology & Therapeutics, University of British Columbia)
    Focus on Stroke

    The role(s) of P2X7 receptor in cerebral ischemia.
    Supervisor: McLarnon, James G. 
  • Crawley, Scott W. (Biochemistry, Queen's University)
    Phosphorylation of caldesmon by Ca2+/calmodulin-dependent kinase III.
    Supervisor: Côté, Graham P. 
  • Cruz, Rani P. (Pathology and Laboratory Medicine, St. Paul's Hospital)
    Elucidating the role of cytochrome p450 enzymes in mitral valve disease.
    Supervisor: McManus, Bruce M. 
  • Dodds, Marnie L. (Physiology and Biophysics, University of Calgary)
    Regulation of cardiac sacoplasmic reticulum by anions.
    Supervisor: Kargacin, Gary J. 
  • Drew, Erin (Medical Genetics, University of British Columbia)
    The role of the stem cell antigen, CD34, on murine mast cells.
    Supervisor: McNagny, Kelly M. 
  • Duval, Martine (Pharmacologie, IRCM)
    Mouvements cellulaires du récepteur VEGFR-2 du VEGF dans les cellules endothéliales.
    Supervisor: Gratton, Jean-Philippe 
  • Esmail, Muneer (Molecular Biology and Biochemistry, Simon Fraser University)
    Target Obesity

    Structural and functional characterization of a novel molecular chaperone associated with Bardet-Biedl syndrome.
    Supervisor: Leroux, Michel R. 
  • Ford, Matthew (Imaging Research Laboratories, Robarts Research Institute)
    Focus on Stroke

    Computational fluid dynamics modeling of endovascular aneurysm therapy.
    Supervisor: Steinman, David A 
  • Franco, Christopher (Laboratory Medicine and Pathobiology, University of Toronto)
    The role of MMP-dependant endothelin processing in vascular smooth muscle contraction and vascular remodeling.
    Supervisor: Bendeck, Michelle P. 
  • Gaskari, Seyed A. (Medicine, University of Calgary)
    Role of endocannabinoid system in the genesis of cirrhotic cardiomypathy.
    Supervisor: Lee, Samuel S. 
  • Gendron, Tania F. (Institute for Biological Sciences, National Research Council of Canada - Winnipeg)
    Focus on Stroke

    The role of transcription factors in neurotoxicity and neuroprotection.
    Supervisor: Morley, Paul 
  • Gharbawie, Omar A. (Canadian Centre for Behavioural Neuroscience, University of Lethbridge)
    Focus on Stroke

    Neural and behavioural correlates of subcortical middle cerebral artery ischemia.
    Supervisor: Whishaw, Ian 
  • Goulet, Julie (Food Science & Nutrition, Université Laval)
    Le mode alimentaire méditerranéen: applicabilité et effets sur santé.
    Supervisor: Lemieux, Simone 
  • Ho, Andrew Tri Van (Molecular and Cellular Biology, University of Toronto)
    Compensatory effects of retinoblastoma protein family and novel apaf1-independent apoptosis in myogenesis.
    Supervisor: Zacksenhaus, Eldad 
  • Hossain, Showkat G.M. (Department of Pathology and Molecular Medicine, McMaster University)
    Role of TDAG51 in detachment-medicated apoptosis and its significance in atherogenesis.
    Supervisor: Austin, Richard C. 
  • Izzi, Luisa (Biochemistry, University of Toronto)
    Smad2 sumoylation modulates the transcriptional activation of FoxH1 target genes during cardiogenesis.
    Supervisor: Attisano, Liliana 
  • Jackson, Dwayne N. (Kinesiology, University of Western Ontario)
    In vivo investigations of gender and sympathetically-mediated vascular remodeling.
    Supervisor: Shoemaker, J. Kevin 
  • Jaswal, Jagdip S. (Pharmacology, University of Alberta)
    Roles of p38 MAPK in myocardial ischemia/reperfusion injury and glucose metabolism.
    Supervisor: Clanachan, Alexander S. 
  • Jia, Xuming (Pharmacology, University of Saskatchewan)
    Target Obesity

    Methylglyoxal induced insulin resistance.
    Supervisor: Wu, Lingyun 
  • Jimenez, Sarah (Physiology, University of Manitoba)
    Genetic regulation of cardioprotective fibroblast growth factors in the adult heart.
    Supervisor: Cattini, Peter A 
  • Khairallah, Maya M.K. (Nutrition, Institut de cardiologie de Montréal)
    Metabolic interventions targeting the dystrophic heart: the potential benefits of medium chain fatty acids.
    Supervisor: Des Rosiers, Christine 
  • Kimmerly, Derek S. (Health Sciences, University of Western Ontario)
    Exercise and central autonomic control of cardiovascular function in human health and disease.
    Supervisor: Shoemaker, J. Kevin 
  • Kolodziejska, Karolina Maria (Cellular & Molecular Biology, Toronto General Hospital)
    c-Myb dependent vascular smooth muscle cell differentiation.
    Supervisor: Husain, Mansoor 
  • Laplante, Marc-André (Physiologie, Université de Montréal)
    Rôle de la voie ERK-MAPK dans l'hypertension induite par l'angiotensine.
    Supervisor: de Champlain, Jacques 
  • Leclerc, Patrice (Pharmacologie, Université de Sherbrooke)
    Modulation de l'activité de liaison du récepteur AT1 par l'oxide nitrique.
    Supervisor: Guillemette, Gaetan 
  • Lee, Joanne S.Y. (Laboratory of Medicine and Pathobiology, University of Toronto)
    Microtubules regulate actin organization and distribution of focal adhesions and adherens junctions.
    Supervisor: Gotlieb, Avrum I. 
  • Leon, Hernando (Pharmacology and Pediatrics, University of Alberta)
    Identification of molecular targets and pharmacological interventions for matrix metalloproteinase-mediated cardiac injury.
    Supervisor: Schulz, Richard 
  • Liu, Yitao (Physiology, University of British Columbia)
    Focus on Stroke

    AMPAR trafficking in models of cerebral ischemia.
    Supervisor: Wang, Yu Tian 
  • MacIntosh, Bradley (Medical Biophysics, Sunnybrook and Women's College Health Sciences Centre)
    Focus on Stroke

    Combining functional imaging and electromyography to assess lower limb deficits in stroke recovery.
    Supervisor: Graham, Simon J. 
  • Major, Geneviève (Kinésiologie, Université de Laval)
    Target Obesity

    Le syndrome d'apnées obstructives du sommeil et les variations de la dépense énergétique.
    Supervisor: Tremblay, Angelo 
  • McGowan, Cheri L. (Kinesiology, McMaster University)
    Isometric handgrip training and arterial pressure reduction: effects and mechanisms.
    Supervisor: McCartney, Neil 
  • Michaud, Sophie Élise (Sciences biomédicales, Université de Montréal)
    Angiogenèse et ischémie vasculaire : Rôle du tabagisme.
    Supervisor: Rivard, Alain 
  • Montague, Patricia (Medicine, McMaster University)
    The study of health assessment and risk in ethnic groups: SHARE offspring.
    Supervisor: Yusuf, Salim 
  • Mullaly, Sarah C. (Physiology & Biophysics, University of Calgary)
    CD14, TLR4, P38 and leukocyte recruitment in shock.
    Supervisor: Kubes, Paul 
  • Murdoch, Barbara (Zoology, University of British Columbia)
    Focus on Stroke

    Molecular identification and characterization of neural stem cells.
    Supervisor: Roskams, Jane Angela 
  • Ploughman, Michelle (Basic Medical Sciences, Memorial University of Newfoundland)
    Focus on Stroke

    The effects of exercise on neuroplasticity, neurotrophins and functional outcome in a rat model of ischemic stroke.
    Supervisor: Corbett, Dale R.
  • Pop, Mihaela (Medical Biophysics, Sunnybrook and Women's College Health Sciences Centre)
    Magnetic resonance guidance of radiofrequency ablation of cardiac arrhythmias.
    Supervisor: Wright, Graham 
  • Pulinilkunnil, Thomas Chacko (Pharmacology and Toxicology, University of British Columbia)
    Effect of diabetes on regulation of cardiac lipoprotein lipase.
    Supervisor: Rodrigues, Brian B. 
  • Purdham, Daniel (Physiology and Pharmacology, University of Western Ontario)
    Target Obesity

    The role of the cardiac leptin system in myocardial ischemia and reperfusion.
    Supervisor: Karmazyn, Morris 
  • Quiniou, Christiane (Pédiatrie, Hôpital Ste-Justine)
    Mécanisme de la mort cellulaire endothéliale microvasculaire causée par le thromboxane.
    Supervisor: Chemtob, Sylvain 
  • Rahmani, Maziar (Pathology and Laboratory Medicine, University of British Columbia)
    Versican gene regulation: molecular mechanisms in valvular and vascular cells.
    Supervisor: McManus, Bruce M. 
  • Rezai, Nana (Pathology and Laboratory Medicine, St. Paul's Hospital)
    Characterization of recipient bone marrow-derived cells in cardiac transplants.
    Supervisor: McManus, Bruce M. 
  • Rose, Patricia Anne (Ophthalmology & Vision Science, Toronto Western Hospital)
    Age-related changes in retinal vascular autoregulation in normal and atherosclerotic patients.
    Supervisor: Hudson, Chris 
  • Roy, Anju A. (Physiology and Pharmacology, University of Western Ontario)
    The mechanism of interaction between RGS2, Gs and the beta2-adrenergic receptor.
    Supervisor: Chidiac, Peter 
  • Sabati, Mohammad R. (Radiology and Clinical Neurosciences, University of Calgary)
    Interactive large field-of-view peripheral magnetic resonance angiography.
    Supervisor: Frayne, Richard 
  • Saini, Harjot K. (Physiology, St. Boniface General Hospital Research Centre)
    Role of angiotensin II in subcellular remodelling in adult cardiomyocytes.
    Supervisor: Dhalla, Naranjan S. 
  • Schneider, Mark (Biochemistry, Queen's University)
    A study of TAFIa mediated suppression of the fibrinolytic cascade.
    Supervisor: Nesheim, Michael E. 
  • Sidhu, Ranjinder S. (Oral Biology, University of Manitoba)
    Significance of oral and phospholipase C-delta 1 interaction.
    Supervisor: Bhullar, Rajinder P. 
  • Sirinyan, Mirna (Pharmacology and Therapeutics, McGill University)
    Retinal endothelial cytotoxic effects of sustained hypercapnia in retinopathy of prematurity.
    Supervisor: Chemtob, Sylvain 
  • Slepkov, Emily R. (Biochemistry, University of Alberta)
    Structure function analysis of the mammalian Na+/H+ exchanger isoform 1.
    Supervisor: Fliegel, Larry 
  • Smith, Robin H. (Department of Pharmacology, Dalhousie University)
    Cardiac excitation - contraction coupling in a transgenic model of heart failure.
    Supervisor: Ferrier, Gregory R. 
  • Song, Dongzhe (Pharmacology & Therapeutics, University of British Columbia)
    Effects of chronic N-acetylcysteine on insulin resistance and blood pressure.
    Supervisor: Pang, Catherine C.Y. 
  • Sun, Hong-Shuo (Physiology and Biophysics, University of Calgary)
    Focus on Stroke

    Neuroprotectove role of K(ARP)-channels of interneurons and neuroglia in stroke using knockout-mice.
    Supervisor: French, Robert J. 
  • Swayze, Richard (Psychiatry, University of British Columbia)
    Focus on Stroke

    Uncoupling of the PKA/AKAP/GluR complex in hypoxia-ischemia.
    Supervisor: El Husseini, Alaa 
  • Sy, Sherwin K.B. (Physiology, McGill University)
    Pharmacological effects on the dynamics of cardiac arrhythmia in cell cultures.
    Supervisor: Glass, Leon 
  • Tomlinson, Juliana J. (Hormones, Growth and Development, Ottawa Health Research Institute)
    Target Obesity

    The identification of transroptional intermediary factor 1 beta in the regulation of steroid induced adipoctye differentiation.
    Supervisor: Haché, Robert J. G. 
  • Tremblay, André (Medecine, Université Laval)
    Etude de la cinetique de l'apolipoproteine B dans l'hypercholesterolemie familiale.
    Supervisor: Couture, Patrick 
  • Trudel, Eric (Neurology & Neurosurgery, Montreal General Hospital)
    Central mechanism underlying circadian variations in the osmoregulation of vasopressin.
    Supervisor: Bourque, Charles W. 
  • Truong, To-Quyen (Sciences Biologiques, Université du Québec à Montréal)
    Rôle des cavéoles dans le métabolisme du cholestérol.
    Supervisor: Brissette, Louise 
  • Villar, Juan C (Cardiology, McMaster University)
    Cardiovascular investigation to assess the markers and outcomes of Chagas' disease.
    Supervisor: Yusuf, Salim 
  • Viscogliosi, Chantal (Medicine, Institut Universitaire de Gériatrie de Sherbrooke)
    Impact d'une atteinte cognitive sur la participation sociale suite à un accident vasculaire cérébral.
    Supervisor: Desrosiers, Johanne 
  • Wang, Jiaxu (CIHR Group in Matrix Dynamics, University of Toronto)
    Regulation of alpha-smooth muscle actin (SMA) by mechanical force in cardiac hypertrophy.
    Supervisor: McCulloch, Christopher A. 
  • Wong, C. Guin Ting (Brain and Behaviour, Hospital for Sick Children)
    PI3 kinase transgenic mice: AMPA receptors and ischemic cell death.
    Supervisor: Snead, Orlando Carter 
  • Yuan, Ji (UBC McDonald Research Laboratories, St. Paul's Hospital)
    Functional analysis of interferon-gamma-inducible protein 10 gene in coxsackievirus B3-induced myocarditis.
    Supervisor: Yang, Decheng 
  • Zaiss, Anne Kathrin (Medicine, University of Calgary)
    Analysis of virus vector mediated apolipoprotein AI gene transfer.
    Supervisor: Wong, Norman C.W. 
  • Zhang, Yiqiang (Research, Montreal Heart Institute)
    Roles of HERG K+ channel in arrhythmias and apoptosis in diabetic cardiomyopathy.
    Supervisor: Wang, Zhiguo 
  • Zhang, Zizhen (Neurology, Montreal General Hospital)
    Signal transduction and modulation of osmoreception in supraoptic neurons.
    Supervisor: Bourque, Charles W.

Nursing Research Fellowships

  • Burns, Susanne L. (School of Nursing, University of British Columbia)
    The accuracy of cardiovascular risk perception in first degree relatives of patients with premature atherosclerosis: does gender matter?
    Supervisor: Ratner, Pamela A. 
  • Colella, Tracey (Faculty of Nursing, University of Calgary)
    The effect of peer support follow-up on CABG patient's recovery.
    Supervisor: King, Kathryn M. 
  • Cortes, Olga L. (School of Nursing, McMaster University)
    Progressive upright mobilization program of patients after acute myocardial infarction in coronary care units.
    Supervisor: Arthur, Heather M. 
  • Green, Theresa L. (Faculty of Nursing, University of Calgary)
    The post-discharge impact of stroke.
    Supervisor: King, Kathryn M. 
  • Harkness, Karen (School of Nursing, McMaster University)
    Anxiety and depression in patients with heart failure & their caregivers: is there a co-variance.
    Supervisor: Arthur, Heather M. 
  • Ireland, Sandra E. (School of Nursing, McMaster University)
    Stroke prevention clinic: relationships among patient satisfaction, health related quality of life and self-management of risk factors.
    Supervisor: Arthur, Heather M. 
  • Keeping, Lisa M. (School of Nursing, McGill University)
    Telehealth (VITAL Program) and psychosocial adjustment of post-CABG patients and their partners.
    Supervisor: Purden, Margaret Ann 
  • McLean, Donna L. (Cardiology, University of Alberta)
    Detection and management of hypertension in patients with diabetes in the community.
    Supervisor: Tsuyuki, Ross T. 
  • Parry, Monica J.E. (Faculty of Nursing, University of Toronto)
    Impact of a home-based intervention on health-related quality of life, function, and symptom management for people following coronary artery bypass graft surgery.
    Supervisor: Watt-Watson, Judy 
  • Rempel, Gwendolyn R. (Faculty of Nursing, University of Alberta)
    Parenting a child with HLHS whose treatment includes the Norwood surgical approach.
    Supervisor: Harrison, Margaret J. 
  • Sanguins, Julianne (Faculty of Nursing, University of Calgary)
    Understanding capacity in first nation people with diabetes and cardiovascular disease.
    Supervisor: Thomlinson, Elizabeth