Heart and Stroke Foundation of Canada Research Programs - 2006 - HSFO Grants-in-Aid and Career Investigator Competition Results

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Heart and Stroke Foundation of Ontario

Results of September 2005 Grant-in-Aid and Career Investigator Competitions

The Heart and Stroke Foundation of Ontario is pleased to announce the scientists from Ontario who were awarded Grant-in-Aid / Career Investigator funding in the September 2005 competition.

These results posted below are to be considered preliminary only. An official letter will be sent to all applicants the week of March 20, 2006, along with the budget / funding details and rankings. Career Investigator awards do not have first year amounts, however the standard stipend applies.

For those awards identified as "pending", funding is encumbered until additional information is provided. Applicants will be contacted in the near future in this regard. Some proposals were not ranked high enough to receive full funding. In such cases, the Foundation has provided a terminal award, in order to assist scientists in maintaining some level of research activity until a re-application can be made.

The Foundation requests that you do not write or telephone with any enquiries before receiving the award letters.

Alter, David A. (Institute for Clinical Evaluation Sciences) Cardiovascular treatment & outcomes disparities among high-risk populations	TYPE	5 Year
	Career Investigator
Alter, David A. (Institute for Clinical Evaluation Sciences) Care gaps among high-risk cardiovascular patients: evaluating the inappropriateness and clinical significance of the "treatment-risk paradox"	TYPE	2 Year
	New (pending)	$86,289
Anand, Sonia (Hamilton General Hospital) EpiDREAM - A prospective cohort study to determine environment and genetic determinants of metabolic syndrome related factors	TYPE	3 Year
	New (pending)	$165,072
Andrew, R. David (Queen's University) Imaging and preventing early stroke damage in intact mammalian neurons	TYPE	3 Year
	Renewal (pending)	$72,613
Austin, Richard C. (McMaster University) Role of endoplasmic reticulum stress in atherothrombotic disease	TYPE	5 Year
	Career Investigator
Bai, Donglin (University of Western Ontario) Connexin mutation and atrial fibrillation	TYPE	2 Year
	New	$71,725
Bartha, Robert (Robarts Research Institute) New metabolic imaging approaches to assess brain tissue viability	TYPE	3 Year
	Renewal	$81,134
Bendeck, Michelle P. (University of Toronto) The role of type VIII collagen in vascular disease	TYPE	2 Year
	New	$85,311
Boffa, Michael B. (Queen's University) The TAFI pathway in thrombolysis: regulation of TAFI activation and role of the platelet pool of TAFI	TYPE	3 Year
	New	$66,139
Bonen, Arend (University of Guelph) Regulation of fatty acid transport in the heart	TYPE	5 Year
	Renewal	$96,323
Boughner, Derek R. (University of Western Ontario) A tissue engineering approach to bioprosthetic heart valve design	TYPE	3 Year
	New	$98,188
Caldwell, Patricia H. (McMaster University) Preferences of patients with advanced heart failure and physicians regarding communication about prognosis and its implications	TYPE	1 Year
	New (pending)	$24,219
Chakrabarti, Subrata (University of Western Ontario) Vasoactive and cardioactive factors in diabetic heart disease	TYPE	2 Year
	New	$75,550
Chauhan, Vijay S. (Toronto General Hospital, UHN) Characterizing ventricular repolarization alternans in human cardiomyopathy	TYPE	1 Year
	Renewal	$35,000
Choong, Karen L.M. (McMaster Children's Hospital) A study of the efficacy of vasopressin in pediatric vasodilatory shock	TYPE	1 Year
	New	$61,623
Ciriello, John (University of Western Ontario) Role of sex steroids in central regulation of arterial pressure	TYPE	1 Year
	Renewal	$35,000
Clarke, Bryan J. (McMaster University) Factor VII as an inhibitor of coagulation, sepsis and cancer	TYPE	2 Year
	New	$82,723
Coles, John G. (Hospital for Sick Children) The regulation of cellular signaling in cardiac progenitor cells	TYPE	2 Year
	New (pending)	$76,039
Connelly, Philip W. (St. Michael's Hospital) Molecular mechanisms for oxidation of high density lipoproteins	TYPE	2 Year
	Renewal	$96,529
Copeland, John W. (University of Ottawa) Role of formin proteins in shear stress-induced cytoskeletal remodeling in endothelial cells	TYPE	2 Year
	New (pending)	$76,480
Cregan, Sean P. (Robarts Research Institute) p53 signaling in oxidative damage induced neuronal apoptosis	TYPE	2 Year
	New (pending)	$72,800
Danckert, James A. (University of Waterloo) Examining the behavioural and neural effects of prisms adaptation in stroke patients suffering from unilateral neglect	TYPE	2 Year
	New (pending)	$42,550
de Kemp, Robert A. (University of Ottawa Heart Institute) Quantitative molecular PET imaging in mouse models of heart disease	TYPE	2 Year
	New (pending)	$70,400
Deeley, Roger (Queen's University) Functional studies of the ATP-binding cassette transporter, ABCA1	TYPE	3 Year
	Renewal (pending)	$92,136
Eubanks, James H. (Toronto Western Hospital, UHN) Methyl DNA-binding factor complexes and neurodegeneration	TYPE	3 Year
	New (pending)	$83,929
Fehlings, Michael G. (Toronto Western Hospital, UHN) The ischemic axon: cross-talk with myelin in K+ channel terms	TYPE	2 Year
	New (pending)	$79,089
Feindel, Christopher M. (Toronto General Hospital, UHN) Erythropoietin and hypertonic saline for cardiac transplant	TYPE	3 Year
	Renewal	$92,959
Feng, Zhong-Ping (University of Toronto) Modulatory mechanisms underlying expression of cardiac voltage-dependent calcium channels	TYPE	3 Year
	Renewal	$62,250
Ferber, Susanne (University of Toronto) Revisiting spatial neglect - implications for theory and rehabilitation	TYPE	2 Year
	New (pending)	$56,003
Ferguson, Stephen G. (Robarts Research Institute) Regulation of G protein-coupled receptor signaling desensitization and resensitization	TYPE	5 Year
	Renewal	$119,696
Floras, John S. (Mount Sinai Hospital) Cardiovascular regulation in men and women with heart failure and hypertension	TYPE	2.5 Year
	Career Investigator
Fremes, Stephen E. (Sunnybrook & Women's College Health Sciences Centre) Unraveling the black box of adverse events in cardiac surgery	TYPE	3 Year
	Renewal (pending)	$90,350
Funk, Colin (Queen's University) Lipoxygenase and cyclooxygenase pathways in cardiovascular disease	TYPE	5 Year
	Career Investigator
Funk, Colin (Queen's University) COX-2 pathway and cardiovascular disease	TYPE	3 Year
	New	$116,208
Gao, Yu-Jing (McMaster University) Perivascular adipose tissue, reactive oxygen species, and hypertension	TYPE	1 Year
	Renewal	$35,000
Gollob, Michael H. (University of Ottawa Heart Institute) Genetic predictors of ventricular arrhythmias in patients with heart failure	TYPE	2 Year
	New (pending)	$50,320
Gollob, Michael H. (University of Ottawa Heart Institute) Pathophysiologic study of the role of AMPK in cardiac arrhythmias, conduction system development, and metabolic cardiomyopathy	TYPE	3 Year
	Renewal	$78,175
Goodman, Jack M. (University of Toronto) Effects of prolonged strenuous exercise on left ventricular function	TYPE	2 Year
	New (pending)	$42,490
Gramolini, Anthony O. (University of Toronto) Molecular basis of PLN regulation and function in cardiac muscle	TYPE	2 Year
	New	$75,929
Grinstein, Sergio (Hospital for Sick Children) Dual role of CD36 in macrophages: atherosclerosis and immune responsiveness	TYPE	4 Year
	Renewal	$80,951
Gross, Gil J. (Hospital for Sick Children) Contractile and electrophysiologic adaptations to constrained heart rate conditions	TYPE	2 Year
	New	$103,631
Grover, Ashok K. (McMaster University) Caloxins: novel inhibitors of plasma membrane calcium pumps	TYPE	2 Year
	New (pending)	$74,608
Gruenwald, Colleen (Hospital for Sick children) Individualized heparin and protamine management in infants undergoing cardiopulmonary bypass for cardiac surgery reduces bleeding and blood transfusion requirements	TYPE	2 Year
	New (pending)	$57,063
Hache, Robert J.G. (Ottawa Health Research Institute) Regulation of human primary preadipocyte differentiation by glucocorticoids	TYPE	3 Year
	Renewal (pending)	$90,138
Hayward, Catherine P. (McMaster University) Structure-function analysis of multimerin 1 proadhesive function	TYPE	3 Year
	Renewal (pending)	$109,206
Hayward, Catherine P. (McMaster University) Studies of the mechanisms involved in generating profibrinolytic and antifibrinolytic human platelets	TYPE	3 Year
	Renewal	$80,462
Hegele, Robert A. (Robarts Research Institute) Genetic determinants of atherosclerosis in ethnic groups: focus on metabolic syndrome	TYPE	5 Year
	Renewal (pending)	$115,467
Heximer, Scott P. (University of Toronto) Defining the role of RGS2 as a mediator of vascular signaling and blood pressure regulation	TYPE	3 Year
	Renewal	$105,639
Holbrook, Anne M. (St. Joseph's Healthcare) Validation and implementation of individualized benefit: harm profiles for optimal warfarin prescribing	TYPE	2 Year
	New	$9,125
Hou, Sheng T. (National Research Council of Canada) Semaphorin-3A's role in axonal degeneration and regeneration following cerebral ischemia	TYPE	3 Year
	Renewal	$59,154
Hough, Margaret R. (Sunnybrook & Women's College Health Sciences Centre) Cardiac repair and regeneration	TYPE	3 Year
	New (pending)	$84,613
Husain, Mansoor (Toronto General Hospital, UHN) Role of glucagon-like peptides in cardiac health and disease	TYPE	3 Year
	New (pending)	$94,000
Igdoura, Suleiman A (McMaster University) Sialidase (neu1) as a novel risk factor for cardiovascular disease	TYPE	2 Year
	Renewal	$74,175
Ikura, Mitsuhiko (Princess Margaret Hospital, UHN) Structural elucidation of intracellular calcium transporters	TYPE	5 Year
	Renewal	$99,575
Irvine, Jane M. (York University) Psychological support for implantable defibrillator patients	TYPE	2 Year
	Renewal (pending)	$91,244
Jaeggi, Edgar T. (Hospital for Sick Children) Intrauterine growth restriction with early and late onset placental insufficiency: impact on myocardial function and arterial compliance	TYPE	2 Year
	New (pending)	$38,260
Kahr, Walter H.A. (Hospital for Sick Children) Secretory granules in human platelets: the role of VPS33B in alpha granule biogenesis	TYPE	2 Year
	New	$78,400
Kanji, Salmaan (Ottawa Health Research Institute) Atrial fibrillation in the intensive care unit: a randomized controlled trial (AFib ICU study)	TYPE	1 Year
	New (pending)	$81,116
Khokha, Rama (Ontario Cancer Institute, UHN) Molecular dissection of the distinct function of TIMP-3 and TIMP-4 in heart disease	TYPE	3 Year
	Renewal	$75,861
Koschinsky, Marlys L. (Queen's University) Mechanisms of atherothrombosis: analysis of lipoprotein and fibrinolytic risk factors	TYPE	5 Year
	Career Investigator
Koschinsky, Marlys L. (Queen's University) The pathophysiology of Lp(a) in the arterial wall: effect of Apo(a) on vascular cell function	TYPE	5 Year
	Renewal	$96,899
Krahn, Andrew D. (University of Western Ontario) Clinical and genetic assessment of primary electrical disease	TYPE	3 Year
	Renewal	$94,976
Lanctot, Krista L. (Sunnybrook & Women's College Health Sciences Centre) The role of cytokine-serotonin interactions in post-stroke depression	TYPE	2 Year
	New (pending)	$57,770
Leong-Poi, Howard M. (St. Michael's Hospital) Site-targeted imaging and delivery of cell-based therapy	TYPE	2 Year
	New (pending)	$73,682
Li, Ren-Ke (Toronto General Hospital, UHN) Restoration of cardiac function: cellular regeneration and matrix reconstruction	TYPE	5 Year
	Career Investigator
Liu, Peter P. (Toronto General Hospital, UHN) Homing signals and cell mobilization in cardiac remodeling post myocardial infarction	TYPE	3 Year
	Renewal	$95,158
Lucas, Alexandra R. (Robarts Research Institute) Serpin regulation of innate immune response and vascular repair	TYPE	3 Year
	Renewal	$60,592
Mak, Alan S. (Queen's University) Cortactin and caldesmon in vascular smooth muscle cell migration and invasion	TYPE	5 Year
	Renewal	$89,313
Marcel, Yves L. (University of Ottawa Heart Institute) The genetic basis of cholesterol efflux defects in hypoalphalipoproteinemia	TYPE	3 Year
	Renewal	$92,583
Marcel, Yves L. (University of Ottawa Heart Institute) Role of GULP in engulfment and cellular cholesterol trafficking	TYPE	1 Year
	Renewal	$35,000
Marsden, Philip A. (University of Toronto) Regulated expression of the human nNOS gene	TYPE	5 Year
	Renewal	$109,203
Maurice, Donald H. (Queen's University) PDEs in blood vessels	TYPE	5 Year
	Career Investigator
McBride, Heidi M. (University of Ottawa Heart Institute) Mechanisms and functions of mitochondrial derived vesicles	TYPE	2 Year
	New	$67,042
McCrindle, Brian W. (Hospital for Sick Children) Identifying determinants and optimizing rehabilitation of physical activity for children after the fontan procedure	TYPE	2 Year
	New (pending)	$62,184
McDermott, John C. (York University) Role of MEF2 interacting proteins in cardiac development and hypertrophy	TYPE	1 Year
	Renewal	$35,000
Melo, Luis Gabriel (Queen's University) Cardiogenic differentiation of mesenchymal stem cells using transcription factors	TYPE	2 Year
	New (pending)	$81,959
Min, Wei-Ping (University of Western Ontario) Protection of heart grafts in transplantation through RNA interference	TYPE	2 Year
	Renewal	$76,140
Newton, Gary E. (Mount Sinai Hospital) Investigations of dietary therapy in human heart failure	TYPE	2 Year
	New (pending)	$57,450
Nurse, Colin A. (McMaster University) Mechanisms regulating asphyxial responses in rat adrenal chromaffin cells	TYPE	4 Year
	Renewal	$92,100
O'Brien, Edward R. (University of Ottawa Heart Institute) Heat shock protein 27, a novel estrogen receptor beta associated protein: role in estrogen signaling and vascular disease	TYPE	3 Year
	New (pending)	$102,200
O'Leary, Deborah D. (Brock University) The effects of body composition on arterial stiffness and baroreflex function in children	TYPE	2 Year
	New (pending)	$47,935
Pandey, Siyaram (University of Windsor) Identification and functional characterization of unique single domain intrabodies against pro-apoptotic proteins and their application in the discovery of novel pharmacophore	TYPE	3 Year
	Renewal	$77,000
Park, David S. (University of Ottawa) Pathways which regulate neuronal death	TYPE	5 Year
	Career Investigator
Park, David S. (University of Ottawa) Oxidative stress and ischemic death	TYPE	2 Year
	New	$68,000
Parker, John D. (Mount Sinai Hospital) Pharmacologic induction of ischemic preconditioning: studies concerning organic nitrates	TYPE	2 Year
	New (pending)	$64,487
Parshuram, Christopher S. (Hospital for Sick Children) PEWS translation project: from retrospective algorithm to real-time bedside tool	TYPE	2 Year
	Renewal	$74,652
Peng, Tianqing (London Health Sciences Centre) PLCgamma/IP3 signaling regulates cardiac TNF-alpha expression in sepsis	TYPE	3 Year
	New (pending)	$93,971
Puri, Mira C. (Sunnybrook & Women's College Health Sciences Centre) Role of endoglin in mammalian cardiovascular development	TYPE	2 Year
	Renewal	$69,349
Rao, Vivek (Toronto General Hospital, UHN) Mechanisms of transplant related vascular injury	TYPE	2 Year
	New	$63,000
Reid, Robert D. (University of Ottawa Heart Institute) An interactive, voice response-mediated, follow-up and triage system for smoking cessation in smokers with CHD	TYPE	3 Year
	New (pending)	$71,625
Richards, Carl D. (McMaster University) Oncostatin M and IL-15 in generation of atherosclerotic plaque formation in APO E-/- mouse model: phenotype of cross of OSM or IL-15 deficient strains with APO E-/-	TYPE	2 Year
	New	$93,002
Ruel, Marc Andre (University of Ottawa Heart Institute) Evaluation of biopolymer delivered EPCs for cardiac repair in a swine model of hibernating myocardium	TYPE	2 Year
	New	$86,364
Schlichter, Lyanne C. (Toronto Western Hospital, UHN) Novel strategies to regulate microglia activation and neurotoxicity	TYPE	3 Year
	Renewal	$96,732
Sheffield, William P. (McMaster University) The clot-targeting properties of natural and engineered antiplasmins	TYPE	3 Year
	Renewal	$80,694
Silverman, Earl D. (Hospital for Sick Children) Role of chronic inflammation and systemic lupus erythematosus-related factors in the development of premature atherosclerosis in pediatric SLE	TYPE	3 Year
	Renewal	$92,945
Silversides, Candice K. (Toronto General Hospital, UHN) Hemodynamics and hormonal changes in pregnant women with cardiac disease: understanding the effects of pregnancy on the diseased heart	TYPE	2 Year
	New (pending)	$37,744
Slack, Ruth (University of Ottawa) Regulation of Mcl1 to treat stroke	TYPE	5 Year
	Renewal	$98,632
Sled, John G. (Hospital for Sick Children) Three dimensional quantification of the placental vascular tree: relationship with normal and abnormal fetal growth and hemodynamics	TYPE	2 Year
	New (pending)	$65,283
Smith, Steven P. (Queen's University) Structural mechanisms of apolipoprotein(a)-ligand interactions: roles in Lp(a) assembly and function	TYPE	1 Year
	Renewal	$35,000
Sparks, Daniel L. (University of Ottawa Heart Institute) Regulation of ApoA-I synthesis and secretion by phoshatidylinositol	TYPE	3 Year
	New	$80,580
Spence, J. David (Robarts Research Institute) 3D Ultrasound phenotypes and vascular risk	TYPE	3 Year
	New	$77,650
Stanimirovic, Danica B. (Inst. for Biological Sciences of CNR) Astrocyte-endothelial cell interactions in hypoxia: role of P1GF in hypoxia-induced brain angiogenesis	TYPE	3 Year
	Renewal	$71,000
Tesson, Frederique (University of Ottawa Heart Institute) Genetic approach to heart failure	TYPE	2 Year
	New	$33,900
Tsushima, Robert G. (University of Toronto) Snare protein modulation of cardiac Kv channels	TYPE	3 Year
	Renewal	$78,002
Tuana, Balwant S. (University of Ottawa) SLMAPs: Sarcolemmal membrane associated proteins and E-C coupling	TYPE	4 Year
	Renewal	$139,652
Tyml, Karel (Lawson Health Research Institute) Microvascular dysfunction in sepsis	TYPE	2 Year
	New (pending)	$92,724
Van Arsdell, Glen S. (Hospital for Sick Children) Analysis of the mechanisms of altered systemic and cerebral oxygen transport in children with hypoplastic left heart syndrome undergoing stage I palliation	TYPE	3 Year
	New (pending)	$87,000
Verma, Subodh (St. Michael's Hospital) RasGRP3: a novel signaling protein and molecular target for endothelial progenitor cell mobilization and neovascularization	TYPE	2 Year
	Renewal	$74,655
Wan, Qi (Toronto Western Hospital, UHN) PTEN suppression-mediated neuroprotection in stroke	TYPE	2 Year
	New (pending)	$76,939
Wang, Hao (University of Western Ontario) Tolerance induction through targeting memory T cells by blocking OX40 signaling pathway in presensitized recipients	TYPE	2 Year
	New	$80,626
Weisel, Richard D. (Toronto General Hospital, UHN) Cardiac regeneration by cell transplantation	TYPE	3 Year
	Renewal (pending)	$69,424
Weitz, Jeffrey I. (McMaster University) Mechanisms of coronary catheter-induced clotting	TYPE	4 Year
	Renewal	$112,788
Werstuck, Geoffrey H. (McMaster University) Mechanisms by which diabetes mellitus promotes the development and progression of atherosclerosis	TYPE	2 Year
	New (pending)	$88,567
Wilson, Gregory J. (Hospital for Sick Children) Chloride channel regulation in myocardial preconditioning	TYPE	5 Year
	Renewal (pending)	$122,503
Yang, Burton B. (Sunnybrook & Women's College Health Sciences Centre) Roles of versican in mediating leukocyte and endothelial cell activites	TYPE	5 Year
	Career Investigator
Yeung, Rae S-M (Hospital for Sick Children) Towards a better understanding of Kawasaki disease	TYPE	2 Year
	New	$79,847
Zaidi, Syed H.E. (University Health Network) Roles of growth differentiation factor 5 and bone morphogenetic protein 4 in cardiovascular diseases	TYPE	2 Year
	New (pending)	$80,040

Dernière mise à jour : ( 07-05-2007 )