Heart and Stroke Foundation of OntarioRelease of Funds for Existing Multi-Year Research Grants
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|
Adeli, Khosrow (Hospital for Sick Children) Molecular mechanisms of apolipoprotein B degradation |
TYPE | 2005 |
|
Renewal |
$117,860 | |
|
Adeli, Khosrow (Hospital for Sick Children) Molecular mechanisms of hepatic VLDL overproduction in insulin resistance |
TYPE | 2007 |
|
Renewal |
$138,235 | |
|
Al-Hesayen, Abdul O. (St. Michael's Hospital) Exploring the role of cGMP in human heart failure |
TYPE | 2007 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Alter, David A. (St. Michael's Hospital) Cardiovascular treatment & outcomes disparities among high-risk populations |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
Anand, Sonia (McMaster University) EpiDREAM - A prospective cohort study to determine environment and genetic determinants of metabolic syndrome related factors |
TYPE | 2006 |
|
New Annual |
$161,495 | |
|
Andrew, R. David (Queen's University) Imaging and preventing early stroke damage in intact mammalian neurons |
TYPE | 2006 |
|
Renewal |
$74,328 | |
|
Askalan, Rand (Hospital for Sick Children) Neuroprotection by inhibitors of apoptosis proteins following neonatal stroke |
TYPE | 2007 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Athale, Uma H. (McMaster University) Evaluation for inherited and acquired prothrombotic defects predisposing to symptomatic thromboembolism in children with acute lymphoblastic leukemia |
TYPE | 2007 |
|
New Annual (Pending) |
$40,351 | |
|
Atzema, Clare (Sunnybrook Health Sciences Center) Emergency department triage and time to ECG: the effect on reperfusion delays for AMI patients |
TYPE | 2007 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Austin, Richard C. (McMaster University) Role of endoplasmic reticulum stress in atherothrombotic disease |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
Austin, Richard C. (McMaster University) Role of the sterol regulatory element-binding proteins in foam cell formation and atherogenesis |
TYPE | 2007 |
|
New Annual |
$94,877 | |
|
Austin, Richard C. (McMaster University) Inhibition of tissue factor procoagulant activity by GRP78 and its role in thrombosis |
TYPE | 2007 |
|
Renewal |
$87,471 | |
|
Backx, Peter H. (University of Toronto) Mechanisms of heart disease |
TYPE | 2004 |
|
Career Investigator |
$87,950 | |
|
Bartha, Robert (Robarts Research Institute) New metabolic imaging approaches to assess brain tissue viability |
TYPE | 2006 |
|
Renewal |
$85,645 | |
|
Beanlands, Rob S. B. (University of Ottawa Heart Institute) Elucidation of metabolic and cellular function alterations in dysfunctional myocardium and their response to therapy |
TYPE | 2007 |
|
Program |
$249,828 | |
|
Belik, Jaques (Hospital for Sick Children) ENOS uncoupling and role of bone morphogenetic protein-9 in the regulation of pulmonary vascular tone during development and following pulmonary hypertension |
TYPE | 2007 |
|
New Annual |
$87,725 | |
|
Bendeck, Michelle P. (University of Toronto) Smooth muscle cell interactions with the extracellular matrix in atherosclerosis |
TYPE | 2004 |
|
Career Investigator |
$87,950 | |
|
Bendeck, Michelle P. (University of Toronto) Discoidin domain receptors (DDR1) in atherosclerosis |
TYPE | 2007 |
|
New Annual |
$84,860 | |
|
Billia, Filio (University of Toronto) Regulation of cardiac muscle growth and proliferation by cytoplasmic p27K1P1 |
TYPE | 2007 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Birnie, David H. (University of Ottawa Heart Institute) Importance of mechanical dyssynchrony and resynchronization therapy in heart failure patients |
TYPE | 2006 |
|
Clinician Scientist (Pending) |
$70,250 | |
|
Boffa, Michael B. (Queen's University) The TAFI pathway in thrombolysis: regulation of TAFI activation and role of the platelet pool of TAFI |
TYPE | 2006 |
|
New Annual |
$90,969 | |
|
Bolz, Steffen-Sebastian (University of Toronto) Mechanisms that regulate the pressure-dependent activation of the sphingosine-1-phosphate signalling pathway in resistance arteries |
TYPE | 2007 |
|
New Annual |
$70,190 | |
|
Bonen, Arend (University of Guelph) Regulation of fatty acid transport in the heart |
TYPE | 2006 |
|
Renewal |
$97,646 | |
|
Bose, Arpita (University of Windsor) Recovery in post-stroke aphasia: psycholinguistics and psychosocial perspective |
TYPE | 2006 |
|
Fellowship |
$47,500 | |
|
Boughner, Derek R. (University of Western Ontario) A tissue engineering approach to bioprosthetic heart valve design |
TYPE | 2006 |
|
New Annual |
$95,398 | |
|
Bradley, Timothy J. (Hospital for Sick Children) Inflammation and atherosclerosis in pediatric rheumatic diseases |
TYPE | 2007 |
|
New Annual |
$66,045 | |
|
Brooks, Dina (University of Toronto) Cardic rehabilitation after stroke |
TYPE | 2006 |
|
Stroke Rehabilitation (Pending) |
$68,479 | |
|
Brouwer, Brenda (Queen's University) Client-centred 'tune-ups': do they enhance physical capacity, mobility function and community reintegration in stroke survivors? |
TYPE | 2006 |
|
Stroke Rehabilitation (Pending) |
$204,206 | |
|
Caldarone, Christopher A. (Hospital for Sick Children) Apoptosis-related mitochondrial dysfunction in the neonate after cardioplegic arrest |
TYPE | 2007 |
|
New Annual (Pending) |
$117,116 | |
|
Cepinskas, Gediminas (London Health Sciences Centre) Cerebrovascular endothelial cell dysfunction in sepsis: role of astrocytes |
TYPE | 2007 |
|
New Annual |
$82,747 | |
|
Chan, Anthony K.C. (McMaster University) Study of the pathogenesis and treatment of pediatric disease related to the hemostatic system |
TYPE | 2005 |
|
Career Investigator |
$87,950 | |
|
Chan, Anthony K.C. (McMaster University) Surface mechanisms of anticoagulant ATH complex |
TYPE | 2007 |
|
Renewal |
$86,139 | |
|
Chauhan, Vijay S. (University Health Network) Characterizing ventricular repolarization alternans in human cardiomyopathy |
TYPE | 2007 |
|
Renewal |
$84,004 | |
|
Chauhan, Vijay S. (University Health Network) Characterizing ventricular repolarization alternans in human cardiomyopathy |
TYPE | 2007 |
|
Clinician Scientist (Pending) |
$70,250 | |
|
Cote, Graham P. (Queen's University) Formation and function of invadopodia in vascular smooth muscle cells |
TYPE | 2007 |
|
Renewal |
$90,618 | |
|
Crowther, Mark A. (McMaster University) Optimizing anticoagulant therapy |
TYPE | 2004 |
|
Career Investigator |
$87,950 | |
|
Crowther, Mark A. (McMaster University) Evaluating the incidence and clinical importance of heparin induced thrombocytopenia in the critically ill |
TYPE | 2007 |
|
New Annual (Pending) |
$65,006 | |
|
Cybulsky, Myron I. (University Health Network) Regional differences in the arterial intima that predispose the artery wall to atherogenesis |
TYPE | 2007 |
|
Renewal |
$104,659 | |
|
Cybulsky, Myron I. (University Health Network) Monocyte recruitment in atherosclerosis |
TYPE | 2007 |
|
Renewal |
$116,845 | |
|
Cybulsky, Myron I. (University Health Network) Initiation of atherosclerosis: mechanisms and cell biology |
TYPE | 2007 |
|
Career Investigator |
$87,950 | |
|
Devereaux, Philip J. (McMaster University) Vascular events in noncardiac surgery patients cohort (VISION) study |
TYPE | 2007 |
|
New Annual (Pending) |
$95,242 | |
|
Drangova, Maria (Robarts Research Institute) Cardiac imaging for therapy guidance and pre-clinical research studies |
TYPE | 2007 |
|
Career Investigator |
$87,950 | |
|
D'Souza, Sudhir J.A. (University of Western Ontario) Integrin-linked kinase and elmo in endothelial migration and phagocytosis |
TYPE | 2007 |
|
New Annual |
$67,744 | |
|
Dumont, Daniel J. (Sunnybrook Health Sciences Center) Molecular studies examining the role of lymphangiogenic signalling in heart disease |
TYPE | 2007 |
|
Renewal |
$84,900 | |
|
Epand, Richard M. (McMaster University) Development of potent antiatherogenic peptides |
TYPE | 2007 |
|
New Annual (Pending) |
$79,250 | |
|
Eubanks, James H. (University Health Network) Methyl DNA-binding factor complexes and neurodegeneration |
TYPE | 2006 |
|
New Annual |
$86,102 | |
|
Feindel, Christopher M. (University Health Network) Erythropoietin and hypertonic saline for cardiac transplant |
TYPE | 2006 |
|
Renewal |
$92,900 | |
|
Feldman, Ross D. (Robarts Research Institute) Determinants of adenylyl cyclase mediated vascular responses |
TYPE | 2007 |
|
New Annual |
$110,850 | |
|
Feldman, Ross D. (Robarts Research Institute) Acute vascular effects of aldosterone |
TYPE | 2007 |
|
New Annual |
$78,016 | |
|
Feng, Qingping (University of Western Ontario) Mechanisms of heart failure |
TYPE | 2005 |
|
Career Investigator |
$87,950 | |
|
Feng, Qingping (London Health Sciences Centre) Cardioprotection by erythropoietin: role of nitric oxide |
TYPE | 2007 |
|
Renewal |
$122,126 | |
|
Feng, Zhong-Ping (University of Toronto) Modulatory mechanisms underlying expression of cardiac voltage-dependent calcium channels |
TYPE | 2006 |
|
Renewal |
$62,250 | |
|
Ferguson, Alastair (Queen's University) Adiponectin actions in autonomic control centres of the brain |
TYPE | 2007 |
|
Renewal |
$120,661 | |
|
Ferguson, Stephen G. (Robarts Research Institute) Regulation of G protein-coupled receptor signaling desensitization and resensitization |
TYPE | 2006 |
|
Renewal |
$123,041 | |
|
Flamengo, Maria F. (University of Western Ontario) Associating baseline levels of medial prefrontal cortex activity with autonomic cardiovascular control. |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
Floras, John S. (University of Toronto) Cardiovascular regulation in men and women with heart failure and hypertension |
TYPE | 2006 |
|
Career Investigator |
$43,975 | |
|
Fremes, Stephen E. (Sunnybrook Health Sciences Center) Unraveling the black box of adverse events in cardiac surgery |
TYPE | 2006 |
|
Renewal |
$88,850 | |
|
Funk, Colin D. (Queen's University) COX-2 pathway and cardiovascular disease |
TYPE | 2006 |
|
New Annual |
$119,470 | |
|
Funk, Colin D. (Queen's University) Lipoxygenase and cyclooxygenase pathways in cardiovascular disease |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
Gaisano, Herbert Y. (University of Toronto) SNARE regulation of cardiac sulfonylurea receptor. a novel drug target for cardiac ischemia |
TYPE | 2007 |
|
Renewal |
$101,479 | |
|
Gao, Yu-Jing (McMaster University) Perivascular adipose tissue, reactive oxygen species and hypertension |
TYPE | 2007 |
|
New Annual |
$74,460 | |
|
Gilbert, Richard E. (St. Michael's Hospital) Pathogenetic role of protein kinase c-beta in diabetic cardiomyopathy: interventional and translational studies |
TYPE | 2007 |
|
New Annual |
$110,085.56 | |
|
Ginsberg, Jeffrey S. (McMaster University) Diagnosis and management of thromboembolic disorders in multiple patient populations |
TYPE | 2007 |
|
Career Investigator |
$87,950 | |
|
Gladstone, David J. (Sunnybrook Health Sciences Center) Stroke prevention for high-risk patients: Identifying barriers and creating solutions |
TYPE | 2006 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Gollob, Michael H. (University of Ottawa Heart Institute) Pathophysiologic study of the role of AMPK in cardiac arrhythmias, conduction system development, and metabolic cardiomyopathy |
TYPE | 2006 |
|
Renewal |
$79,531 | |
|
Gollob, Michael H. (University of Ottawa Heart Institute) Genetic determination of atrial fibrillation |
TYPE | 2006 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Gorczynski, Reginald M. (University Health Network) Regulation of transplant rejection and inflammation in CD200tg and CD200R KO mice |
TYPE | 2007 |
|
New Annual |
$92,208 | |
|
Gotlieb, Avrum I. (University Health Network) Cell biology of heart valve interstitial cells |
TYPE | 2007 |
|
New Annual |
$90,516 | |
|
Graham, Charles H. (Queen's University) Mechanisms regulating the development and pathophysiology of pre-eclamptic hypertension |
TYPE | 2007 |
|
Renewal |
$96,792 | |
|
Grinstein, Sergio (Hospital for Sick Children) Dual role of CD36 in macrophages: atherosclerosis and immune responsiveness |
TYPE | 2006 |
|
Renewal |
$87,596 | |
|
Gross, Gil J. (Hospital for Sick Children) Ventricular repolarization in bradycardic electrical remodeling |
TYPE | 2007 |
|
Renewal |
$89,674 | |
|
Gross, Peter L. (McMaster University) Defining how atorvastatin inhibits platelets |
TYPE | 2007 |
|
New Annual |
$75,148 | |
|
Grover, Ashok K. (McMaster University) Effects of reactive oxygen on Na-Ca exchange in coronary artery |
TYPE | 2007 |
|
Renewal |
$101,514 | |
|
Gupta, Radhey S. (McMaster University) Studies on mammalian adenosine kinase and its inhibitors |
TYPE | 2007 |
|
Renewal |
$87,879 | |
|
Haas, Tara L. (York University) The regulation of angiogenic factors by shear stress |
TYPE | 2007 |
|
New Annual |
$79,750 | |
|
Hache, Robert J.G. (Ottawa Health Research Institute) Regulation of human primary preadipocyte differentiation by glucocorticoids |
TYPE | 2006 |
|
Renewal |
$93,779 | |
|
Han, Kristina (Queen's University) The cellular biochemistry of apolipoprotein(a) secretion: relationship between Apo(a) size and secretion efficiency |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
Harper, Mary-Ellen (University of Ottawa) Novel AMPK-gamma mutations in humans: implications for skeletal muscle energy metabolism |
TYPE | 2007 |
|
New Annual (Pending) |
$100,324 | |
|
Hayward, Catherine P. (McMaster University) Studies of novel platelet and vascular secretory proteins |
TYPE | 2005 |
|
Career Investigator |
$87,950 | |
|
Hayward, Catherine P. (McMaster University) Structure-function analysis of multimerin 1 proadhesive function |
TYPE | 2006 |
|
Renewal |
$93,251 | |
|
Hayward, Catherine P. (McMaster University) Studies of the mechanisms involved in generating profibrinolytic and antifibrinolytic human platelets |
TYPE | 2006 |
|
Renewal |
$82,299 | |
|
Hegele, Robert A. (Robarts Research Institute) Phenomics and genomics of atherosclerosis in monogenic metabolic syndrome |
TYPE | 2007 |
|
Renewal |
$110,723 | |
|
Hegele, Robert A. (Robarts Research Institute) Genomics of hypertriglyceridemia |
TYPE | 2007 |
|
New Annual (Pending) |
$110,372 | |
|
Heximer, Scott P. (University of Toronto) Defining the role of RGS2 as a mediator of vascular signaling and blood pressure regulation |
TYPE | 2006 |
|
Renewal |
$109,623 | |
|
Hou, Sheng T. (University of Ottawa) Semaphorin-3A's role in axonal degeneration and regeneration following cerebral ischemia |
TYPE | 2006 |
|
Renewal |
$65,392 | |
|
Hough, Margaret R. (Sunnybrook Health Sciences Center) Cardiac repair and regeneration |
TYPE | 2006 |
|
New Annual |
$91,113 | |
|
Huff, Murray W. (University of Western Ontario) Regulation of ApoB metabolism: relationship to atherosclerosis |
TYPE | 2005 |
|
Renewal |
$136,879 | |
|
Huff, Murray W. (Robarts Research Institute) Cellular Programs and Responses in Atherosclerosis |
TYPE | 2006 |
|
Program |
$250,000 | |
|
Husain, Mansoor (University of Toronto) Molecular regulation of vascular smooth muscle cell proliferation and contractility |
TYPE | 2004 |
|
Career Investigator |
$87,950 | |
|
Husain, Mansoor (University Health Network) Role of glucagon-like peptides in cardiac health and disease |
TYPE | 2006 |
|
New Annual |
$116,909 | |
|
Hutchison, James Sanders (Hospital for Sick Children) Adhesion receptors following global cerebral ischemia: Role of adhesion receptor blockade/knockout and hypothermia therapy |
TYPE | 2007 |
|
New Annual (Pending) |
$71,380 | |
|
Ikura, Mitsuhiko (University Health Network) Structural elucidation of intracellular calcium transporters |
TYPE | 2006 |
|
Renewal |
$102,377 | |
|
Kahr, Walter H.A. (Hospital for Sick Children) The role of VPS33B in platelet alpha granule formation |
TYPE | 2006 |
|
Clinician Scientist (Pending) |
$70,250 | |
|
Karmazyn, Morris (University of Western Ontario) Modulation of cardiomyocyte hypertrophy by nitric oxide and endothelin-1 in the aging myocardium |
TYPE | 2005 |
|
Renewal |
$102,526 | |
|
Karmazyn, Morris (University of Western Ontario) Role of adenosine in myocardial hypertrophy and heart failure |
TYPE | 2007 |
|
New Annual |
$95,610 | |
|
Kawaja, Michael David (Queen's University) Evaluating phenotypic changes in cerebral vessels of stroke-prone spontaneously hypertensive rats: a pilot proteomic investigation |
TYPE | 2007 |
|
New Annual (Pending) |
$68,042 | |
|
Keeley, Fred W. (Hospital for Sick Children) Recombinantly expressed polypeptides of human elastin as a novel tool for investigations of the structure, self-assembly and properties of elastin-like materials |
TYPE | 2004 |
|
Renewal |
$115,923 | |
|
Kelton, John G. (McMaster University) Platelet-mediated acute thrombotic disorders |
TYPE | 2005 |
|
Renewal |
$149,413 | |
|
Khokha, Rama (University Health Network) Molecular dissection of the distinct function of TIMP-3 and TIMP-4 in heart disease |
TYPE | 2006 |
|
Renewal |
$75,861 | |
|
Ko, Dennis T. (Sunnybrook Health Sciences Center) Appropriateness and necessity of coronary angiogram |
TYPE | 2006 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Koschinsky, Marlys L. (Queen's University) Interaction of Lp(a) with the plasminogen system: mechanisms and pathophysiological consequences |
TYPE | 2005 |
|
Renewal (Pending) |
$101,667 | |
|
Koschinsky, Marlys L. (Queen's University) The pathophysiology of Lp(a) in the arterial wall: effect of Apo(a) on vascular cell function |
TYPE | 2006 |
|
Renewal |
$100,600 | |
|
Koschinsky, Marlys L. (Queen's University) Mechanisms of atherothrombosis: analysis of lipoprotein and fibrinolytic risk factors |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
Krahn, Andrew D. (University of Western Ontario) Clinical and genetic assessment of primary electrical disease |
TYPE | 2006 |
|
Renewal |
$97,231 | |
|
Kutryk, Michael J. B. (St. Michael's Hospital) Novel application of progenitor endothelial cells |
TYPE | 2006 |
|
Clinician Scientist (Pending) |
$70,250 | |
|
Langille, B. Lowell (University of Toronto) Cell Biology of Atherosclerosis |
TYPE | 2005 |
|
Program |
$250,000 | |
|
Langille, B. Lowell (University Health Network) Arterial responses to hemodynamic stresses |
TYPE | 2007 |
|
Renewal |
$91,308 | |
|
Langille, B. Lowell (University Health Network) Cadherins and regulation of smooth muscle cell function |
TYPE | 2007 |
|
Renewal |
$125,957 | |
|
Letarte, Michelle V. (Hospital for Sick Children) Role of endoglin in normal vasculature and in the pathology of HHT |
TYPE | 2005 |
|
Renewal |
$95,321 | |
|
Levin, Mindy F. (University of Ottawa) Optimizing arm motor recovery in stroke |
TYPE | 2007 |
|
New Annual (Pending) |
$33,100 | |
|
Li, Ren-Ke (University Health Network) Restoration of cardiac function: cellular regeneration and matrix reconstruction |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
Li, Ren-Ke (University Health Network) Matrix modulation is required to restore cardiac function after cell therapy |
TYPE | 2007 |
|
Renewal |
$94,497 | |
|
Linkins, Lori-Ann (McMaster University) Improving the diagnosis of heparin-induced thrombocytopenia: utility of the 4T's score and evaluation of new rapid assays |
TYPE | 2007 |
|
New Annual (Pending) |
$103,722 | |
|
Liu, Peter P. (University Health Network) "Danger signal", cell injury and "innate immune response" in regulating inflammation in cardiovascular disease |
TYPE | 2005 |
|
Renewal (Pending) |
$111,062 | |
|
Liu, Peter P. (University Health Network) Homing signals and cell mobilization in cardiac remodeling post myocardial infarction |
TYPE | 2006 |
|
Renewal |
$98,341 | |
|
Logan, Alexander G. (Mount Sinai Hospital) Self-monitoring of blood pressure in primary care in older (45+ years) diabetic patients with uncontrolled systolic hypertension |
TYPE | 2006 |
|
Elevated Systolic (Pending) |
$204,003 | |
|
Lucas, Alexandra R. (Robarts Research Institute) Serpin regulation of innate immune response and vascular repair |
TYPE | 2006 |
|
Renewal |
$78,892 | |
|
Mak, Alan S. (Queen's University) Cortactin and caldesmon in vascular smooth muscle cell migration and invasion |
TYPE | 2006 |
|
Renewal |
$96,865 | |
|
Marcel, Yves L. (University of Ottawa Heart Institute) The genetic basis of cholesterol efflux defects in hypoalphalipoproteinemia |
TYPE | 2006 |
|
Renewal |
$94,746 | |
|
Marsden, Philip A. (University of Toronto) Post-transcriptional regulation of eNOS expression |
TYPE | 2005 |
|
Renewal |
$95,069 | |
|
Marsden, Philip A. (University of Toronto) Regulated expression of the human nNOS gene |
TYPE | 2006 |
|
Renewal |
$112,578 | |
|
Maurice, Donald H. (Queen's University) PDEs in blood vessels |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
McCulloch, Christopher A. (University of Toronto) Regulation of myofibroblast differentiation by mechanical loading |
TYPE | 2007 |
|
Renewal |
$98,082 | |
|
McNicholl, Eric T. (McMaster University) Structural basis for the cAMP signal translation in PKA by NMR |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
McPherson, Ruth (University of Ottawa Heart Institute) Genetic determinants of HDL-C |
TYPE | 2007 |
|
New Annual (Pending) |
$134,607 | |
|
Megeney, Lynn A. (Ottawa Health Research Institute) Caspase mediated induction of cardiac hypertrophy |
TYPE | 2007 |
|
New Annual (Pending) |
$81,066 | |
|
Milne, Ross W. (University of Ottawa Heart Institute) Advanced glycation end products and diabetic atherosclerosis |
TYPE | 2007 |
|
Renewal |
$69,794 | |
|
Morris, Catherine E. (Ottawa Health Research Institute) The mechanosensitivity of pacemaker channels |
TYPE | 2007 |
|
New Annual |
$80,914 | |
|
Myers, Martin G. (Sunnybrook Health Sciences Center) Automated office blood pressure measurement |
TYPE | 2005 |
|
Elevated Systolic (Pending) |
$358,043 | |
|
Nag, Sukriti (University Health Network) Regulation of cerebrovascular homeostasis and repair by angiogenic factors |
TYPE | 2007 |
|
Renewal |
$89,595 | |
|
Nesheim, Michael E. (Queen's University) The activation of TAFI and the properties of TAFIa |
TYPE | 2005 |
|
Renewal (Pending) |
$90,699 | |
|
Nowacki, Nathaniel B. (York University) Regulation of MEF2 activity in cardiac myocytes |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
Nurse, Colin A. (McMaster University) Mechanisms regulating asphyxial responses in rat adrenal chromaffin cells |
TYPE | 2006 |
|
Renewal |
$84,325 | |
|
Ofosu, Frederick A. (McMaster University) Platelet-derived serine proteases and platelet activation |
TYPE | 2007 |
|
Renewal |
$70,398 | |
|
Opas, Michal J. (University of Toronto) Calreticulin: cell and developmental biology |
TYPE | 2007 |
|
Renewal |
$107,923 | |
|
Opavsky, Mary Anne (Hospital for Sick Children) Heart failure and the coxsackie-adenovirus receptor (CAR): insights through a novel heart targeted CAR transgenic mouse |
TYPE | 2007 |
|
Renewal |
$92,114 | |
|
Opavsky, Mary Anne (Hospital for Sick Children) The coxsackie-adenovirus receptor in heart infection and heart failure |
TYPE | 2007 |
|
Clinician Scientist (Pending) |
$70,250 | |
|
Pak, Melissa (Queen's University) Dysfunctional muscle blood flow regulation during exercise in type II diabetes |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
Pandey, Siyaram (University of Windsor) Identification and functional characterization of unique single domain intrabodies against pro-apoptotic proteins and their application in the discovery of novel pharmacophore |
TYPE | 2006 |
|
Renewal |
$61,000 | |
|
Pang, Stephen C. (Queen's University) Hypoxia inducible expression of atrial natriuretic peptide: a potential preemptive therapy for myocardial infarction |
TYPE | 2007 |
|
Renewal |
$84,452 | |
|
Park, David S. (University of Ottawa) Mechanisms of delayed death in stroke |
TYPE | 2004 |
|
Renewal |
$80,600 | |
|
Park, David S. (Ottawa Health Research Institute) Pathways which regulate neuronal death |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
Parker, John D. (University of Toronto) Clinical studies concerning nitrate pharmacology and autonomic physiology in congestive heart failure |
TYPE | 2007 |
|
Career Investigator |
$87,950 | |
|
Parkinson, John (Hospital for Sick Children) A combined theoretical/experimental approach to understanding sequence-structure-function relationships in elastin |
TYPE | 2007 |
|
Renewal |
$58,548 | |
|
Peng, Tianqing (London Health Sciences Centre) PLCgamma/IP3 signaling regulates cardiac TNF-alpha expression in sepsis |
TYPE | 2006 |
|
New Annual |
$98,805 | |
|
Pickering, J. Geoffrey (Robarts Research Institute) Regulation of smooth muscle cell differentiation and longevity |
TYPE | 2005 |
|
Renewal |
$107,295 | |
|
Popovic, Milos R. (Toronto Rehabilitation Institute) Functional electrical stimulation-assisted walking: enhancement of voluntary walking function among persons with severe hemiplegia post stroke |
TYPE | 2006 |
|
Stroke Rehabilitation (Pending) |
$32,265 | |
|
Radisic, Milica (University of Toronto) Peptide modified photocrosslinkable chitosan for cell therapy in myocardial infarction |
TYPE | 2007 |
|
New Annual |
$52,154 | |
|
Rand, Margaret L. (Hospital for Sick Children) The procoagulant surface of activated platelets: persistence in vitro and in vivo |
TYPE | 2007 |
|
Renewal |
$87,521 | |
|
Reid, Robert D. (University of Ottawa Heart Institute) An interactive, voice response-mediated, follow-up and triage system for smoking cessation in smokers with CHD |
TYPE | 2006 |
|
New Annual |
$33,312 | |
|
Reid, Robert D. (University of Ottawa Heart Institute) Efficacy and cost-effectiveness of behavioural counselling for exercise behaviour in men and women following AMI and PCI |
TYPE | 2007 |
|
Renewal |
$73,375 | |
|
Reid, Robert D. (University of Ottawa Heart Institute) A program to reduce cardiovascular risk among family members of patients with coronary heart disease |
TYPE | 2007 |
|
New Annual (Pending) |
$93,050 | |
|
Robinson, Lisa A. (Hospital for Sick Children) Regulation of the membrane-anchored chemokine, fractalkine, by thromboxane A2 |
TYPE | 2007 |
|
Renewal |
$89,480 | |
|
Rochon, Elizabeth A (University of Toronto) Understanding the behavioural, neural and communicative changes underlying the treatment for anomia in aphasia |
TYPE | 2007 |
|
Renewal |
$92,328 | |
|
Rodger, Marc A. (Ottawa Health Research Institute) Thrombophilia and placenta mediated pregnancy complications |
TYPE | 2007 |
|
Career Investigator |
$87,950 | |
|
Roy, Eric A. (University of Waterloo) Neuropsychological profiles and neuroanatomic correlates of limb apraxia |
TYPE | 2007 |
|
Renewal |
$69,864 | |
|
Rush, James W.E. (University of Waterloo) Vascular endothelium adaptations to hypertension and exercise |
TYPE | 2007 |
|
Renewal |
$73,831 | |
|
Sandig, Martin (University of Western Ontario) Integrin signaling in monocyte transendothelial migration |
TYPE | 2007 |
|
New Annual |
$84,265 | |
|
Schlichter, Lyanne C. (University Health Network) Novel strategies to regulate microglia activation and neurotoxicity |
TYPE | 2006 |
|
Renewal |
$86,963 | |
|
Seibert, Tara A. (University of Ottawa) Understanding the vascular protective mechanisms of an estrogen- inducible protein using gene expression profiling |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
Shaughnessy, Stephen G. (McMaster University) Mechanisms of vascular calcification in diabetes mellitus |
TYPE | 2007 |
|
New Annual (Pending) |
$78,729 | |
|
Sheffield, William P. (McMaster University) The clot-targeting properties of natural and engineered antiplasmins |
TYPE | 2006 |
|
Renewal |
$83,308 | |
|
Sherifali, Diana T. (McMaster University) Appraisal of a community approach to facilitated self-management of diabetes mellitus |
TYPE | 2007 |
|
Nursing Fellowship |
$59,000 | |
|
Shikatani, Eric A. (York University) Cellular mechanisms underlying corticosterone-dependent inhibition of angiogenesis |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
Silverman, Earl D. (Hospital for Sick Children) Role of chronic inflammation and systemic lupus erythematosus-related factors in the development of premature atherosclerosis in pediatric SLE |
TYPE | 2006 |
|
Renewal |
$136,843 | |
|
Simmons, Craig A. (University of Toronto) The role of extracellular matrix biomechanics in aortic valve sclerosis |
TYPE | 2007 |
|
New Annual |
$83,235 | |
|
Siu, Samuel C. (University Health Network) Neurodevelopmental outcomes in offsprings of women with heart disease |
TYPE | 2007 |
|
Renewal |
$40,070 | |
|
Slack, Ruth (Ottawa Health Research Institute) Regulation of Mcl1 to treat stroke |
TYPE | 2006 |
|
Renewal |
$101,388 | |
|
Slack, Ruth (Ottawa Health Research Institute) Mitochondrial dynamics in neuronal injury |
TYPE | 2007 |
|
New Annual |
$109,773.20 | |
|
Smith, Steven P. (Queen's University) Lipoprotein(a) in atherosclerosis: assembly and interaction with extracellular matrix proteins |
TYPE | 2007 |
|
Renewal |
$130,119 | |
|
Sorisky, Alexander (Ottawa Health Research Institute) Pro-atherogenic responses of human adipocytes to TSH |
TYPE | 2007 |
|
Renewal |
$93,039 | |
|
Sparks, Daniel L. (University of Ottawa Heart Institute) Regulation of ApoA-I synthesis and secretion by phoshatidylinositol |
TYPE | 2006 |
|
New Annual |
$101,836 | |
|
Spears, Julian (St. Michael's Hospital) International, prospective, multi-center study of radiographic and clinical events in the management of cerebral aneurysms >= 1cm |
TYPE | 2006 |
|
Clinician Scientist (Pending) |
$64,000 | |
|
Spence, J. David (Robarts Research Institute) 3D Ultrasound phenotypes and vascular risk |
TYPE | 2006 |
|
New Annual |
$100,027 | |
|
Spencer, Frederick A. (McMaster University) Clinical epidemiology and management of cardiovascular and venous thromboembolic disease |
TYPE | 2007 |
|
Career Investigator |
$87,950 | |
|
Spencer, Frederick A. (McMaster University) Fortinos Distinguished Scientist Award |
TYPE | 2007 |
|
Fortinos Award |
$10,000 | |
|
Stanimirovic, Danica B. (University of Ottawa) Astrocyte-endothelial cell interactions in hypoxia: role of P1GF in hypoxia-induced brain angiogenesis |
TYPE | 2006 |
|
Renewal |
$73,586 | |
|
Steinman, David A. (University of Toronto) Image-based modelling of hemodynamics and cerebrovascular disease |
TYPE | 2004 |
|
Career Investigator |
$87,950 | |
|
Sugita, Shuzo (University Health Network) Roles for CAPS1 in loading, storage and secretion of catecholamines in pheochromocytoma cells |
TYPE | 2007 |
|
New Annual |
$64,500 | |
|
Sun, Jiangfeng (University of Ottawa Heart Institute) Role of estrogen receptor beta in endothelial progenitor cell-mediated vascualr repair |
TYPE | 2007 |
|
Fellowship |
$47,500 | |
|
Suskin, Neville (London Health Sciences Centre) Comprehensive cardiac rehabilitation programming for patients following transient ischemic attack |
TYPE | 2007 |
|
New Annual (Pending) |
$126,745 | |
|
Suuronen, Erik J. (University of Ottawa Heart Institute) Recruitment of endogenous circulating progenitor cells for cardiac regeneration using acellular tissue-engineered biomatrices |
TYPE | 2007 |
|
New Annual |
$94,333 | |
|
Sweeney, Gary (York University) Direct effects of adiponectin on cardiomyocytes |
TYPE | 2007 |
|
Renewal |
$70,250 | |
|
Truong, Kevin (University of Toronto) Deciphering Ca2+ signaling between subcellular organelles using fluorescent protein biosensors expressed in living cells |
TYPE | 2007 |
|
New Annual |
$51,600 | |
|
Tsushima, Robert G. (York University) Snare protein modulation of cardiac Kv channels |
TYPE | 2006 |
|
Renewal |
$80,925 | |
|
Tu, Jack V. (Sunnybrook Health Sciences Center) Improving the quality of heart and stroke care in Canada |
TYPE | 2005 |
|
Career Investigator |
$87,950 | |
|
Tuana, Balwant S. (University of Ottawa) SLMAPs: Sarcolemmal membrane associated proteins and E-C coupling |
TYPE | 2006 |
|
Renewal |
$142,667 | |
|
Van Arsdell, Glen S. (Hospital for Sick Children) Analysis of the mechanisms of altered systemic and cerebral oxygen transport in children with hypoplastic left heart syndrome undergoing stage I palliation |
TYPE | 2006 |
|
New Annual (Pending) |
$89,328 | |
|
Van Arsdell, Glen S. (Hospital for Sick Children) The influence of postoperative systemic oxygen transport on neurologic outcomes in infants undergoing the Norwood procedure with a modified blalock-taussig shunt or a right ventricle-to-pulmonary artery shunt |
TYPE | 2007 |
|
New Annual (Pending) |
$59,150 | |
|
Verma, Subodh (St. Michael's Hospital) ACE2: Novel regulator of endothelial function and atherosclerosis |
TYPE | 2007 |
|
New Annual |
$105,809 | |
|
Waddell, Thomas K. (University Health Network) The role of galectin-3 in xenograft rejection |
TYPE | 2007 |
|
New Annual (Pending) |
$91,950 | |
|
Wade, Terrance J. (Brock University) Social Determinants of Child Hypertension |
TYPE | 2007 |
|
Social Determinants (Pending) |
$100,085 | |
|
Wang, Hui Di (Brock University) Reactive oxygen species mediates angiotensin II induced ET-1 release from vascular adventitial fibroblasts |
TYPE | 2007 |
|
New Annual |
$57,010 | |
|
Ward, Christopher A. (Queen's University) Cell-based gene therapy strategy to enhance neovascularization and healing of infarcted myocardium |
TYPE | 2007 |
|
Renewal |
$92,952 | |
|
Warkentin, Theodore E. (McMaster University) Heparin-induced thrombocytopenia |
TYPE | 2007 |
|
Renewal |
$101,854 | |
|
Weisel, Richard D. (University Health Network) Cardiac regeneration by cell transplantation |
TYPE | 2006 |
|
Renewal |
$72,075 | |
|
Weisel, Richard D. (University Health Network) Cardiac regeneration: improving the response to injury |
TYPE | 2007 |
|
Renewal |
$77,182 | |
|
Weitz, Jeffrey I. (McMaster University) Mechanisms of coronary catheter-induced clotting |
TYPE | 2006 |
|
Renewal |
$116,670 | |
|
Wells, Philip S. (Ottawa Health Research Institute) Thrombophilia: from bench to bedside to health economics and policy |
TYPE | 2004 |
|
Program |
$250,000 | |
|
Wen, Xiao-Yan (University Health Network) Investigation of lysophospatidic acid (LPA) generation and platelet function in newly developed lpdlr phospholipase deficient mice |
TYPE | 2007 |
|
New Annual |
$87,232 | |
|
Werstuck, Geoffrey H. (McMaster University) Investigating the role of glycogen synthase kinase (GSK)-3 in atherogenesis |
TYPE | 2007 |
|
Renewal |
$82,688 | |
|
Wijeysundera, Duminda N. (University Health Network) The EPIC (evaluating perioperative ischemia reduction by clonidine) study: a randomized, triple-blinded, placebo-controlled trial of combining clonidine with chronic beta-blockade in intermediate-to-high risk non-cardiac surgery |
TYPE | 2007 |
|
New Annual (Pending) |
$40,085 | |
|
Yang, Burton B. (Sunnybrook Health Sciences Center) Roles of versican in mediating leukocyte and endothelial cell activites |
TYPE | 2006 |
|
Career Investigator |
$87,950 | |
|
Yang, Kaiping (University of Western Ontario) Early-life origins of visceral adiposity |
TYPE | 2007 |
|
New Annual |
$85,192 | |
|
Yao, Zemin (University of Ottawa Heart Institute) Interrelationship between hepatic lipase expression, proinflammatory cytokines, and HDL metabolism |
TYPE | 2007 |
|
Renewal |
$86,360 | |
|
Yao, Zemin (University of Ottawa) Analysis of non-truncation apoB mutations associated with human familial hypobetalipoproteinemia |
TYPE | 2007 |
|
Renewal |
$82,538 | |
|
Yarmo, Michelle (University of Ottawa) Macrophage-adipose cell interactions in obesity and cardiovascular disease |
TYPE | 2007 |
|
Master's Studentship (Pending) |
$18,000 | |
|
Zandstra, Peter W. (University of Toronto) Controlling bioreactor condition to optimize regenerative potential of cardiomyocytes |
TYPE | 2007 |
|
New Annual |
$89,725 | |
|
Zhang, Xia (University of Ottawa) Poststroke treatment with cannabinoids for promoting neuronal regeneration |
TYPE | 2007 |
|
New Annual |
$59,670 | |
|
Zhang, Zhu-Xu (London Health Sciences Centre) Therapeutic potential and mechanism of double-negative regulatory T (DN-Treg) cells mediated tolerance in heart transplantation |
TYPE | 2007 |
|
New Annual |
$78,294 | |
|
Zimmerman, Deborah L. (Ottawa Health Research Institute) Control of hypertension in end stage renal disease, a randomized cross-over study comparing daily hemofiltration to conventional hemodialysis |
TYPE | 2007 |
|
New Annual (Pending) |
$53,327 |