Heart and Stroke Foundation of Ontario

Release of Funds for Existing Multi-Year Research Grants
and Personnel Awards for the term of July 1, 2008 to
June 30, 2009

The Heart and Stroke Foundation of Ontario is pleased to announce confirmation of budget commitment on existing multi-year grants-in-aid and personnel awards as indicated below. An official letter will also be sent to all grant recipients shortly. For those awards identified as "pending"", funding is encumbered until additional information is provided.

Additionally, for projects that were identified as being "applied" or "clinically oriented" in the September 2006 competition, funding is encumbered pending the May 15, 2008 Progress Report. For all other awards, please refer to your award letter for details. 
September 2007 Competition Funding Decisions
The funding decisions for the September 2007 competition will be announced by March 15, 2008 on the national website www.hsf.ca/research.

Adeli, Khosrow (Hospital for Sick Children)

Molecular mechanisms of apolipoprotein B degradation

TYPE 2005
Renewal
$117,860

Adeli, Khosrow (Hospital for Sick Children)

Molecular mechanisms of hepatic VLDL overproduction in insulin resistance

TYPE 2007
Renewal
$138,235

Al-Hesayen, Abdul O. (St. Michael's Hospital)

Exploring the role of cGMP in human heart failure

TYPE 2007
Clinician Scientist
(Pending)
$64,000

Alter, David A. (St. Michael's Hospital)

Cardiovascular treatment & outcomes disparities among high-risk populations

TYPE 2006
Career Investigator
$87,950

Anand, Sonia (McMaster University)

EpiDREAM - A prospective cohort study to determine environment and genetic determinants of metabolic syndrome related factors

TYPE 2006
New Annual
$161,495

Andrew, R. David (Queen's University)

Imaging and preventing early stroke damage in intact mammalian neurons

TYPE 2006
Renewal
$74,328

Askalan, Rand (Hospital for Sick Children)

Neuroprotection by inhibitors of apoptosis proteins following neonatal stroke

TYPE 2007
Clinician Scientist
(Pending)
$64,000

Athale, Uma H. (McMaster University)

Evaluation for inherited and acquired prothrombotic defects predisposing to symptomatic thromboembolism in children with acute lymphoblastic leukemia

TYPE 2007
New Annual
(Pending)
$40,351

Atzema, Clare (Sunnybrook Health Sciences Center)

Emergency department triage and time to ECG: the effect on reperfusion delays for AMI patients

TYPE 2007
Clinician Scientist
(Pending)
$64,000

Austin, Richard C. (McMaster University)

Role of endoplasmic reticulum stress in atherothrombotic disease

TYPE 2006
Career Investigator
$87,950

Austin, Richard C. (McMaster University)

Role of the sterol regulatory element-binding proteins in foam cell formation and atherogenesis

TYPE 2007
New Annual
$94,877

Austin, Richard C. (McMaster University)

Inhibition of tissue factor procoagulant activity by GRP78 and its role in thrombosis

TYPE 2007
Renewal
$87,471

Backx, Peter H. (University of Toronto)

Mechanisms of heart disease

TYPE 2004
Career Investigator
$87,950

Bartha, Robert (Robarts Research Institute)

New metabolic imaging approaches to assess brain tissue viability

TYPE 2006
Renewal
$85,645

Beanlands, Rob S. B. (University of Ottawa Heart Institute)

Elucidation of metabolic and cellular function alterations in dysfunctional myocardium and their response to therapy

TYPE 2007
Program
$249,828

Belik, Jaques (Hospital for Sick Children)

ENOS uncoupling and role of bone morphogenetic protein-9 in the regulation of pulmonary vascular tone during development and following pulmonary hypertension

TYPE 2007
New Annual
$87,725

Bendeck, Michelle P. (University of Toronto)

Smooth muscle cell interactions with the extracellular matrix in atherosclerosis

TYPE 2004
Career Investigator
$87,950

Bendeck, Michelle P. (University of Toronto)

Discoidin domain receptors (DDR1) in atherosclerosis

TYPE 2007
New Annual
$84,860

Billia, Filio (University of Toronto)

Regulation of cardiac muscle growth and proliferation by cytoplasmic p27K1P1

TYPE 2007
Clinician Scientist
(Pending)
$64,000

Birnie, David H. (University of Ottawa Heart Institute)

Importance of mechanical dyssynchrony and resynchronization therapy in heart failure patients

TYPE 2006
Clinician Scientist
(Pending)
$70,250

Boffa, Michael B. (Queen's University)

The TAFI pathway in thrombolysis: regulation of TAFI activation and role of the platelet pool of TAFI

TYPE 2006
New Annual
$90,969

Bolz, Steffen-Sebastian (University of Toronto)

Mechanisms that regulate the pressure-dependent activation of the sphingosine-1-phosphate signalling pathway in resistance arteries

TYPE 2007
New Annual
$70,190

Bonen, Arend (University of Guelph)

Regulation of fatty acid transport in the heart

TYPE 2006
Renewal
$97,646

Bose, Arpita (University of Windsor)

Recovery in post-stroke aphasia: psycholinguistics and psychosocial perspective

TYPE 2006
Fellowship
$47,500

Boughner, Derek R. (University of Western Ontario)

A tissue engineering approach to bioprosthetic heart valve design

TYPE 2006
New Annual
$95,398

Bradley, Timothy J. (Hospital for Sick Children)

Inflammation and atherosclerosis in pediatric rheumatic diseases

TYPE 2007
New Annual
$66,045

Brooks, Dina (University of Toronto)

Cardic rehabilitation after stroke

TYPE 2006
Stroke Rehabilitation
(Pending)
$68,479

Brouwer, Brenda (Queen's University)

Client-centred 'tune-ups': do they enhance physical capacity, mobility function and community reintegration in stroke survivors?

TYPE 2006
Stroke Rehabilitation
(Pending)
$204,206

Caldarone, Christopher A. (Hospital for Sick Children)

Apoptosis-related mitochondrial dysfunction in the neonate after cardioplegic arrest

TYPE 2007
New Annual
(Pending)
$117,116

Cepinskas, Gediminas (London Health Sciences Centre)

Cerebrovascular endothelial cell dysfunction in sepsis: role of astrocytes

TYPE 2007
New Annual
$82,747

Chan, Anthony K.C. (McMaster University)

Study of the pathogenesis and treatment of pediatric disease related to the hemostatic system

TYPE 2005
Career Investigator
$87,950

Chan, Anthony K.C. (McMaster University)

Surface mechanisms of anticoagulant ATH complex

TYPE 2007
Renewal
$86,139

Chauhan, Vijay S. (University Health Network)

Characterizing ventricular repolarization alternans in human cardiomyopathy

TYPE 2007
Renewal
$84,004

Chauhan, Vijay S. (University Health Network)

Characterizing ventricular repolarization alternans in human cardiomyopathy

TYPE 2007
Clinician Scientist
(Pending)
$70,250

Cote, Graham P. (Queen's University)

Formation and function of invadopodia in vascular smooth muscle cells

TYPE 2007
Renewal
$90,618

Crowther, Mark A. (McMaster University)

Optimizing anticoagulant therapy

TYPE 2004
Career Investigator
$87,950

Crowther, Mark A. (McMaster University)

Evaluating the incidence and clinical importance of heparin induced thrombocytopenia in the critically ill

TYPE 2007
New Annual
(Pending)
$65,006

Cybulsky, Myron I. (University Health Network)

Regional differences in the arterial intima that predispose the artery wall to atherogenesis

TYPE 2007
Renewal
$104,659

Cybulsky, Myron I. (University Health Network)

Monocyte recruitment in atherosclerosis

TYPE 2007
Renewal
$116,845

Cybulsky, Myron I. (University Health Network)

Initiation of atherosclerosis: mechanisms and cell biology

TYPE 2007
Career Investigator
$87,950

Devereaux, Philip J. (McMaster University)

Vascular events in noncardiac surgery patients cohort (VISION) study

TYPE 2007
New Annual
(Pending)
$95,242

Drangova, Maria (Robarts Research Institute)

Cardiac imaging for therapy guidance and pre-clinical research studies

TYPE 2007
Career Investigator
$87,950

D'Souza, Sudhir J.A. (University of Western Ontario)

Integrin-linked kinase and elmo in endothelial migration and phagocytosis

TYPE 2007
New Annual
$67,744

Dumont, Daniel J. (Sunnybrook Health Sciences Center)

Molecular studies examining the role of lymphangiogenic signalling in heart disease

TYPE 2007
Renewal
$84,900

Epand, Richard M. (McMaster University)

Development of potent antiatherogenic peptides

TYPE 2007
New Annual
(Pending)
$79,250

Eubanks, James H. (University Health Network)

Methyl DNA-binding factor complexes and neurodegeneration

TYPE 2006
New Annual
$86,102

Feindel, Christopher M. (University Health Network)

Erythropoietin and hypertonic saline for cardiac transplant

TYPE 2006
Renewal
$92,900

Feldman, Ross D. (Robarts Research Institute)

Determinants of adenylyl cyclase mediated vascular responses

TYPE 2007
New Annual
$110,850

Feldman, Ross D. (Robarts Research Institute)

Acute vascular effects of aldosterone

TYPE 2007
New Annual
$78,016

Feng, Qingping (University of Western Ontario)

Mechanisms of heart failure

TYPE 2005
Career Investigator
$87,950

Feng, Qingping (London Health Sciences Centre)

Cardioprotection by erythropoietin: role of nitric oxide

TYPE 2007
Renewal
$122,126

Feng, Zhong-Ping (University of Toronto)

Modulatory mechanisms underlying expression of cardiac voltage-dependent calcium channels

TYPE 2006
Renewal
$62,250

Ferguson, Alastair (Queen's University)

Adiponectin actions in autonomic control centres of the brain

TYPE 2007
Renewal
$120,661

Ferguson, Stephen G. (Robarts Research Institute)

Regulation of G protein-coupled receptor signaling desensitization and resensitization

TYPE 2006
Renewal
$123,041

Flamengo, Maria F. (University of Western Ontario)

Associating baseline levels of medial prefrontal cortex activity with autonomic cardiovascular control.

TYPE 2007
Master's Studentship
(Pending)
$18,000

Floras, John S. (University of Toronto)

Cardiovascular regulation in men and women with heart failure and hypertension

TYPE 2006
Career Investigator
$43,975

Fremes, Stephen E. (Sunnybrook Health Sciences Center)

Unraveling the black box of adverse events in cardiac surgery

TYPE 2006
Renewal
$88,850

Funk, Colin D. (Queen's University)

COX-2 pathway and cardiovascular disease

TYPE 2006
New Annual
$119,470

Funk, Colin D. (Queen's University)

Lipoxygenase and cyclooxygenase pathways in cardiovascular disease

TYPE 2006
Career Investigator
$87,950

Gaisano, Herbert Y. (University of Toronto)

SNARE regulation of cardiac sulfonylurea receptor. a novel drug target for cardiac ischemia

TYPE 2007
Renewal
$101,479

Gao, Yu-Jing (McMaster University)

Perivascular adipose tissue, reactive oxygen species and hypertension

TYPE 2007
New Annual
$74,460

Gilbert, Richard E. (St. Michael's Hospital)

Pathogenetic role of protein kinase c-beta in diabetic cardiomyopathy: interventional and translational studies

TYPE 2007
New Annual
$110,085.56

Ginsberg, Jeffrey S. (McMaster University)

Diagnosis and management of thromboembolic disorders in multiple patient populations

TYPE 2007
Career Investigator
$87,950

Gladstone, David J. (Sunnybrook Health Sciences Center)

Stroke prevention for high-risk patients: Identifying barriers and creating solutions

TYPE 2006
Clinician Scientist
(Pending)
$64,000

Gollob, Michael H. (University of Ottawa Heart Institute)

Pathophysiologic study of the role of AMPK in cardiac arrhythmias, conduction system development, and metabolic cardiomyopathy

TYPE 2006
Renewal
$79,531

Gollob, Michael H. (University of Ottawa Heart Institute)

Genetic determination of atrial fibrillation

TYPE 2006
Clinician Scientist
(Pending)
$64,000

Gorczynski, Reginald M. (University Health Network)

Regulation of transplant rejection and inflammation in CD200tg and CD200R KO mice

TYPE 2007
New Annual
$92,208

Gotlieb, Avrum I. (University Health Network)

Cell biology of heart valve interstitial cells

TYPE 2007
New Annual
$90,516

Graham, Charles H. (Queen's University)

Mechanisms regulating the development and pathophysiology of pre-eclamptic hypertension

TYPE 2007
Renewal
$96,792

Grinstein, Sergio (Hospital for Sick Children)

Dual role of CD36 in macrophages: atherosclerosis and immune responsiveness

TYPE 2006
Renewal
$87,596

Gross, Gil J. (Hospital for Sick Children)

Ventricular repolarization in bradycardic electrical remodeling

TYPE 2007
Renewal
$89,674

Gross, Peter L. (McMaster University)

Defining how atorvastatin inhibits platelets

TYPE 2007
New Annual
$75,148

Grover, Ashok K. (McMaster University)

Effects of reactive oxygen on Na-Ca exchange in coronary artery

TYPE 2007
Renewal
$101,514

Gupta, Radhey S. (McMaster University)

Studies on mammalian adenosine kinase and its inhibitors

TYPE 2007
Renewal
$87,879

Haas, Tara L. (York University)

The regulation of angiogenic factors by shear stress

TYPE 2007
New Annual
$79,750

Hache, Robert J.G. (Ottawa Health Research Institute)

Regulation of human primary preadipocyte differentiation by glucocorticoids

TYPE 2006
Renewal
$93,779

Han, Kristina (Queen's University)

The cellular biochemistry of apolipoprotein(a) secretion: relationship between Apo(a) size and secretion efficiency

TYPE 2007
Master's Studentship
(Pending)
$18,000

Harper, Mary-Ellen (University of Ottawa)

Novel AMPK-gamma mutations in humans: implications for skeletal muscle energy metabolism

TYPE 2007
New Annual
(Pending)
$100,324

Hayward, Catherine P. (McMaster University)

Studies of novel platelet and vascular secretory proteins

TYPE 2005
Career Investigator
$87,950

Hayward, Catherine P. (McMaster University)

Structure-function analysis of multimerin 1 proadhesive function

TYPE 2006
Renewal
$93,251

Hayward, Catherine P. (McMaster University)

Studies of the mechanisms involved in generating profibrinolytic and antifibrinolytic human platelets

TYPE 2006
Renewal
$82,299

Hegele, Robert A. (Robarts Research Institute)

Phenomics and genomics of atherosclerosis in monogenic metabolic syndrome

TYPE 2007
Renewal
$110,723

Hegele, Robert A. (Robarts Research Institute)

Genomics of hypertriglyceridemia

TYPE 2007
New Annual
(Pending)
$110,372

Heximer, Scott P. (University of Toronto)

Defining the role of RGS2 as a mediator of vascular signaling and blood pressure regulation

TYPE 2006
Renewal
$109,623

Hou, Sheng T. (University of Ottawa)

Semaphorin-3A's role in axonal degeneration and regeneration following cerebral ischemia

TYPE 2006
Renewal
$65,392

Hough, Margaret R. (Sunnybrook Health Sciences Center)

Cardiac repair and regeneration

TYPE 2006
New Annual
$91,113

Huff, Murray W. (University of Western Ontario)

Regulation of ApoB metabolism: relationship to atherosclerosis

TYPE 2005
Renewal
$136,879

Huff, Murray W. (Robarts Research Institute)

Cellular Programs and Responses in Atherosclerosis

TYPE 2006
Program
$250,000

Husain, Mansoor (University of Toronto)

Molecular regulation of vascular smooth muscle cell proliferation and contractility

TYPE 2004
Career Investigator
$87,950

Husain, Mansoor (University Health Network)

Role of glucagon-like peptides in cardiac health and disease

TYPE 2006
New Annual
$116,909

Hutchison, James Sanders (Hospital for Sick Children)

Adhesion receptors following global cerebral ischemia: Role of adhesion receptor blockade/knockout and hypothermia therapy

TYPE 2007
New Annual
(Pending)
$71,380

Ikura, Mitsuhiko (University Health Network)

Structural elucidation of intracellular calcium transporters

TYPE 2006
Renewal
$102,377

Kahr, Walter H.A. (Hospital for Sick Children)

The role of VPS33B in platelet alpha granule formation

TYPE 2006
Clinician Scientist
(Pending)
$70,250

Karmazyn, Morris (University of Western Ontario)

Modulation of cardiomyocyte hypertrophy by nitric oxide and endothelin-1 in the aging myocardium

TYPE 2005
Renewal
$102,526

Karmazyn, Morris (University of Western Ontario)

Role of adenosine in myocardial hypertrophy and heart failure

TYPE 2007
New Annual
$95,610

Kawaja, Michael David (Queen's University)

Evaluating phenotypic changes in cerebral vessels of stroke-prone spontaneously hypertensive rats: a pilot proteomic investigation

TYPE 2007
New Annual
(Pending)
$68,042

Keeley, Fred W. (Hospital for Sick Children)

Recombinantly expressed polypeptides of human elastin as a novel tool for investigations of the structure, self-assembly and properties of elastin-like materials

TYPE 2004
Renewal
$115,923

Kelton, John G. (McMaster University)

Platelet-mediated acute thrombotic disorders

TYPE 2005
Renewal
$149,413

Khokha, Rama (University Health Network)

Molecular dissection of the distinct function of TIMP-3 and TIMP-4 in heart disease

TYPE 2006
Renewal
$75,861

Ko, Dennis T. (Sunnybrook Health Sciences Center)

Appropriateness and necessity of coronary angiogram

TYPE 2006
Clinician Scientist
(Pending)
$64,000

Koschinsky, Marlys L. (Queen's University)

Interaction of Lp(a) with the plasminogen system: mechanisms and pathophysiological consequences

TYPE 2005
Renewal
(Pending)
$101,667

Koschinsky, Marlys L. (Queen's University)

The pathophysiology of Lp(a) in the arterial wall: effect of Apo(a) on vascular cell function

TYPE 2006
Renewal
$100,600

Koschinsky, Marlys L. (Queen's University)

Mechanisms of atherothrombosis: analysis of lipoprotein and fibrinolytic risk factors

TYPE 2006
Career Investigator
$87,950

Krahn, Andrew D. (University of Western Ontario)

Clinical and genetic assessment of primary electrical disease

TYPE 2006
Renewal
$97,231

Kutryk, Michael J. B. (St. Michael's Hospital)

Novel application of progenitor endothelial cells

TYPE 2006
Clinician Scientist
(Pending)
$70,250

Langille, B. Lowell (University of Toronto)

Cell Biology of Atherosclerosis

TYPE 2005
Program
$250,000

Langille, B. Lowell (University Health Network)

Arterial responses to hemodynamic stresses

TYPE 2007
Renewal
$91,308

Langille, B. Lowell (University Health Network)

Cadherins and regulation of smooth muscle cell function

TYPE 2007
Renewal
$125,957

Letarte, Michelle V. (Hospital for Sick Children)

Role of endoglin in normal vasculature and in the pathology of HHT

TYPE 2005
Renewal
$95,321

Levin, Mindy F. (University of Ottawa)

Optimizing arm motor recovery in stroke

TYPE 2007
New Annual
(Pending)
$33,100

Li, Ren-Ke (University Health Network)

Restoration of cardiac function: cellular regeneration and matrix reconstruction

TYPE 2006
Career Investigator
$87,950

Li, Ren-Ke (University Health Network)

Matrix modulation is required to restore cardiac function after cell therapy

TYPE 2007
Renewal
$94,497

Linkins, Lori-Ann (McMaster University)

Improving the diagnosis of heparin-induced thrombocytopenia: utility of the 4T's score and evaluation of new rapid assays

TYPE 2007
New Annual
(Pending)
$103,722

Liu, Peter P. (University Health Network)

"Danger signal", cell injury and "innate immune response" in regulating inflammation in cardiovascular disease

TYPE 2005
Renewal
(Pending)
$111,062

Liu, Peter P. (University Health Network)

Homing signals and cell mobilization in cardiac remodeling post myocardial infarction

TYPE 2006
Renewal
$98,341

Logan, Alexander G. (Mount Sinai Hospital)

Self-monitoring of blood pressure in primary care in older (45+ years) diabetic patients with uncontrolled systolic hypertension

TYPE 2006
Elevated Systolic
(Pending)
$204,003

Lucas, Alexandra R. (Robarts Research Institute)

Serpin regulation of innate immune response and vascular repair

TYPE 2006
Renewal
$78,892

Mak, Alan S. (Queen's University)

Cortactin and caldesmon in vascular smooth muscle cell migration and invasion

TYPE 2006
Renewal
$96,865

Marcel, Yves L. (University of Ottawa Heart Institute)

The genetic basis of cholesterol efflux defects in hypoalphalipoproteinemia

TYPE 2006
Renewal
$94,746

Marsden, Philip A. (University of Toronto)

Post-transcriptional regulation of eNOS expression

TYPE 2005
Renewal
$95,069

Marsden, Philip A. (University of Toronto)

Regulated expression of the human nNOS gene

TYPE 2006
Renewal
$112,578

Maurice, Donald H. (Queen's University)

PDEs in blood vessels

TYPE 2006
Career Investigator
$87,950

McCulloch, Christopher A. (University of Toronto)

Regulation of myofibroblast differentiation by mechanical loading

TYPE 2007
Renewal
$98,082

McNicholl, Eric T. (McMaster University)

Structural basis for the cAMP signal translation in PKA by NMR

TYPE 2007
Master's Studentship
(Pending)
$18,000

McPherson, Ruth (University of Ottawa Heart Institute)

Genetic determinants of HDL-C

TYPE 2007
New Annual
(Pending)
$134,607

Megeney, Lynn A. (Ottawa Health Research Institute)

Caspase mediated induction of cardiac hypertrophy

TYPE 2007
New Annual
(Pending)
$81,066

Milne, Ross W. (University of Ottawa Heart Institute)

Advanced glycation end products and diabetic atherosclerosis

TYPE 2007
Renewal
$69,794

Morris, Catherine E. (Ottawa Health Research Institute)

The mechanosensitivity of pacemaker channels

TYPE 2007
New Annual
$80,914

Myers, Martin G. (Sunnybrook Health Sciences Center)

Automated office blood pressure measurement

TYPE 2005
Elevated Systolic
(Pending)
$358,043

Nag, Sukriti (University Health Network)

Regulation of cerebrovascular homeostasis and repair by angiogenic factors

TYPE 2007
Renewal
$89,595

Nesheim, Michael E. (Queen's University)

The activation of TAFI and the properties of TAFIa

TYPE 2005
Renewal
(Pending)
$90,699

Nowacki, Nathaniel B. (York University)

Regulation of MEF2 activity in cardiac myocytes

TYPE 2007
Master's Studentship
(Pending)
$18,000

Nurse, Colin A. (McMaster University)

Mechanisms regulating asphyxial responses in rat adrenal chromaffin cells

TYPE 2006
Renewal
$84,325

Ofosu, Frederick A. (McMaster University)

Platelet-derived serine proteases and platelet activation

TYPE 2007
Renewal
$70,398

Opas, Michal J. (University of Toronto)

Calreticulin: cell and developmental biology

TYPE 2007
Renewal
$107,923

Opavsky, Mary Anne (Hospital for Sick Children)

Heart failure and the coxsackie-adenovirus receptor (CAR): insights through a novel heart targeted CAR transgenic mouse

TYPE 2007
Renewal
$92,114

Opavsky, Mary Anne (Hospital for Sick Children)

The coxsackie-adenovirus receptor in heart infection and heart failure

TYPE 2007
Clinician Scientist
(Pending)
$70,250

Pak, Melissa (Queen's University)

Dysfunctional muscle blood flow regulation during exercise in type II diabetes

TYPE 2007
Master's Studentship
(Pending)
$18,000

Pandey, Siyaram (University of Windsor)

Identification and functional characterization of unique single domain intrabodies against pro-apoptotic proteins and their application in the discovery of novel pharmacophore

TYPE 2006
Renewal
$61,000

Pang, Stephen C. (Queen's University)

Hypoxia inducible expression of atrial natriuretic peptide: a potential preemptive therapy for myocardial infarction

TYPE 2007
Renewal
$84,452

Park, David S. (University of Ottawa)

Mechanisms of delayed death in stroke

TYPE 2004
Renewal
$80,600

Park, David S. (Ottawa Health Research Institute)

Pathways which regulate neuronal death

TYPE 2006
Career Investigator
$87,950

Parker, John D. (University of Toronto)

Clinical studies concerning nitrate pharmacology and autonomic physiology in congestive heart failure

TYPE 2007
Career Investigator
$87,950

Parkinson, John (Hospital for Sick Children)

A combined theoretical/experimental approach to understanding sequence-structure-function relationships in elastin

TYPE 2007
Renewal
$58,548

Peng, Tianqing (London Health Sciences Centre)

PLCgamma/IP3 signaling regulates cardiac TNF-alpha expression in sepsis

TYPE 2006
New Annual
$98,805

Pickering, J. Geoffrey (Robarts Research Institute)

Regulation of smooth muscle cell differentiation and longevity

TYPE 2005
Renewal
$107,295

Popovic, Milos R. (Toronto Rehabilitation Institute)

Functional electrical stimulation-assisted walking: enhancement of voluntary walking function among persons with severe hemiplegia post stroke

TYPE 2006
Stroke Rehabilitation
(Pending)
$32,265

Radisic, Milica (University of Toronto)

Peptide modified photocrosslinkable chitosan for cell therapy in myocardial infarction

TYPE 2007
New Annual
$52,154

Rand, Margaret L. (Hospital for Sick Children)

The procoagulant surface of activated platelets: persistence in vitro and in vivo

TYPE 2007
Renewal
$87,521

Reid, Robert D. (University of Ottawa Heart Institute)

An interactive, voice response-mediated, follow-up and triage system for smoking cessation in smokers with CHD

TYPE 2006
New Annual
$33,312

Reid, Robert D. (University of Ottawa Heart Institute)

Efficacy and cost-effectiveness of behavioural counselling for exercise behaviour in men and women following AMI and PCI

TYPE 2007
Renewal
$73,375

Reid, Robert D. (University of Ottawa Heart Institute)

A program to reduce cardiovascular risk among family members of patients with coronary heart disease

TYPE 2007
New Annual
(Pending)
$93,050

Robinson, Lisa A. (Hospital for Sick Children)

Regulation of the membrane-anchored chemokine, fractalkine, by thromboxane A2

TYPE 2007
Renewal
$89,480

Rochon, Elizabeth A (University of Toronto)

Understanding the behavioural, neural and communicative changes underlying the treatment for anomia in aphasia

TYPE 2007
Renewal
$92,328

Rodger, Marc A. (Ottawa Health Research Institute)

Thrombophilia and placenta mediated pregnancy complications

TYPE 2007
Career Investigator
$87,950

Roy, Eric A. (University of Waterloo)

Neuropsychological profiles and neuroanatomic correlates of limb apraxia

TYPE 2007
Renewal
$69,864

Rush, James W.E. (University of Waterloo)

Vascular endothelium adaptations to hypertension and exercise

TYPE 2007
Renewal
$73,831

Sandig, Martin (University of Western Ontario)

Integrin signaling in monocyte transendothelial migration

TYPE 2007
New Annual
$84,265

Schlichter, Lyanne C. (University Health Network)

Novel strategies to regulate microglia activation and neurotoxicity

TYPE 2006
Renewal
$86,963

Seibert, Tara A. (University of Ottawa)

Understanding the vascular protective mechanisms of an estrogen- inducible protein using gene expression profiling

TYPE 2007
Master's Studentship
(Pending)
$18,000

Shaughnessy, Stephen G. (McMaster University)

Mechanisms of vascular calcification in diabetes mellitus

TYPE 2007
New Annual
(Pending)
$78,729

Sheffield, William P. (McMaster University)

The clot-targeting properties of natural and engineered antiplasmins

TYPE 2006
Renewal
$83,308

Sherifali, Diana T. (McMaster University)

Appraisal of a community approach to facilitated self-management of diabetes mellitus

TYPE 2007
Nursing Fellowship
$59,000

Shikatani, Eric A. (York University)

Cellular mechanisms underlying corticosterone-dependent inhibition of angiogenesis

TYPE 2007
Master's Studentship
(Pending)
$18,000

Silverman, Earl D. (Hospital for Sick Children)

Role of chronic inflammation and systemic lupus erythematosus-related factors in the development of premature atherosclerosis in pediatric SLE

TYPE 2006
Renewal
$136,843

Simmons, Craig A. (University of Toronto)

The role of extracellular matrix biomechanics in aortic valve sclerosis

TYPE 2007
New Annual
$83,235

Siu, Samuel C. (University Health Network)

Neurodevelopmental outcomes in offsprings of women with heart disease

TYPE 2007
Renewal
$40,070

Slack, Ruth (Ottawa Health Research Institute)

Regulation of Mcl1 to treat stroke

TYPE 2006
Renewal
$101,388

Slack, Ruth (Ottawa Health Research Institute)

Mitochondrial dynamics in neuronal injury

TYPE 2007
New Annual
$109,773.20

Smith, Steven P. (Queen's University)

Lipoprotein(a) in atherosclerosis: assembly and interaction with extracellular matrix proteins

TYPE 2007
Renewal
$130,119

Sorisky, Alexander (Ottawa Health Research Institute)

Pro-atherogenic responses of human adipocytes to TSH

TYPE 2007
Renewal
$93,039

Sparks, Daniel L. (University of Ottawa Heart Institute)

Regulation of ApoA-I synthesis and secretion by phoshatidylinositol

TYPE 2006
New Annual
$101,836

Spears, Julian (St. Michael's Hospital)

International, prospective, multi-center study of radiographic and clinical events in the management of cerebral aneurysms >= 1cm

TYPE 2006
Clinician Scientist
(Pending)
$64,000

Spence, J. David (Robarts Research Institute)

3D Ultrasound phenotypes and vascular risk

TYPE 2006
New Annual
$100,027

Spencer, Frederick A. (McMaster University)

Clinical epidemiology and management of cardiovascular and venous thromboembolic disease

TYPE 2007
Career Investigator
$87,950

Spencer, Frederick A. (McMaster University)

Fortinos Distinguished Scientist Award

TYPE 2007
Fortinos Award
$10,000

Stanimirovic, Danica B. (University of Ottawa)

Astrocyte-endothelial cell interactions in hypoxia: role of P1GF in hypoxia-induced brain angiogenesis

TYPE 2006
Renewal
$73,586

Steinman, David A. (University of Toronto)

Image-based modelling of hemodynamics and cerebrovascular disease

TYPE 2004
Career Investigator
$87,950

Sugita, Shuzo (University Health Network)

Roles for CAPS1 in loading, storage and secretion of catecholamines in pheochromocytoma cells

TYPE 2007
New Annual
$64,500

Sun, Jiangfeng (University of Ottawa Heart Institute)

Role of estrogen receptor beta in endothelial progenitor cell-mediated vascualr repair

TYPE 2007
Fellowship
$47,500

Suskin, Neville (London Health Sciences Centre)

Comprehensive cardiac rehabilitation programming for patients following transient ischemic attack

TYPE 2007
New Annual
(Pending)
$126,745

Suuronen, Erik J. (University of Ottawa Heart Institute)

Recruitment of endogenous circulating progenitor cells for cardiac regeneration using acellular tissue-engineered biomatrices

TYPE 2007
New Annual
$94,333

Sweeney, Gary (York University)

Direct effects of adiponectin on cardiomyocytes

TYPE 2007
Renewal
$70,250

Truong, Kevin (University of Toronto)

Deciphering Ca2+ signaling between subcellular organelles using fluorescent protein biosensors expressed in living cells

TYPE 2007
New Annual
$51,600

Tsushima, Robert G. (York University)

Snare protein modulation of cardiac Kv channels

TYPE 2006
Renewal
$80,925

Tu, Jack V. (Sunnybrook Health Sciences Center)

Improving the quality of heart and stroke care in Canada

TYPE 2005
Career Investigator
$87,950

Tuana, Balwant S. (University of Ottawa)

SLMAPs: Sarcolemmal membrane associated proteins and E-C coupling

TYPE 2006
Renewal
$142,667

Van Arsdell, Glen S. (Hospital for Sick Children)

Analysis of the mechanisms of altered systemic and cerebral oxygen transport in children with hypoplastic left heart syndrome undergoing stage I palliation

TYPE 2006
New Annual
(Pending)
$89,328

Van Arsdell, Glen S. (Hospital for Sick Children)

The influence of postoperative systemic oxygen transport on neurologic outcomes in infants undergoing the Norwood procedure with a modified blalock-taussig shunt or a right ventricle-to-pulmonary artery shunt

TYPE 2007
New Annual
(Pending)
$59,150

Verma, Subodh (St. Michael's Hospital)

ACE2: Novel regulator of endothelial function and atherosclerosis

TYPE 2007
New Annual
$105,809

Waddell, Thomas K. (University Health Network)

The role of galectin-3 in xenograft rejection

TYPE 2007
New Annual
(Pending)
$91,950

Wade, Terrance J. (Brock University)

Social Determinants of Child Hypertension

TYPE 2007
Social Determinants
(Pending)
$100,085

Wang, Hui Di (Brock University)

Reactive oxygen species mediates angiotensin II induced ET-1 release from vascular adventitial fibroblasts

TYPE 2007
New Annual
$57,010

Ward, Christopher A. (Queen's University)

Cell-based gene therapy strategy to enhance neovascularization and healing of infarcted myocardium

TYPE 2007
Renewal
$92,952

Warkentin, Theodore E. (McMaster University)

Heparin-induced thrombocytopenia

TYPE 2007
Renewal
$101,854

Weisel, Richard D. (University Health Network)

Cardiac regeneration by cell transplantation

TYPE 2006
Renewal
$72,075

Weisel, Richard D. (University Health Network)

Cardiac regeneration: improving the response to injury

TYPE 2007
Renewal
$77,182

Weitz, Jeffrey I. (McMaster University)

Mechanisms of coronary catheter-induced clotting

TYPE 2006
Renewal
$116,670

Wells, Philip S. (Ottawa Health Research Institute)

Thrombophilia: from bench to bedside to health economics and policy

TYPE 2004
Program
$250,000

Wen, Xiao-Yan (University Health Network)

Investigation of lysophospatidic acid (LPA) generation and platelet function in newly developed lpdlr phospholipase deficient mice

TYPE 2007
New Annual
$87,232

Werstuck, Geoffrey H. (McMaster University)

Investigating the role of glycogen synthase kinase (GSK)-3 in atherogenesis

TYPE 2007
Renewal
$82,688

Wijeysundera, Duminda N. (University Health Network)

The EPIC (evaluating perioperative ischemia reduction by clonidine) study: a randomized, triple-blinded, placebo-controlled trial of combining clonidine with chronic beta-blockade in intermediate-to-high risk non-cardiac surgery

TYPE 2007
New Annual
(Pending)
$40,085

Yang, Burton B. (Sunnybrook Health Sciences Center)

Roles of versican in mediating leukocyte and endothelial cell activites

TYPE 2006
Career Investigator
$87,950

Yang, Kaiping (University of Western Ontario)

Early-life origins of visceral adiposity

TYPE 2007
New Annual
$85,192

Yao, Zemin (University of Ottawa Heart Institute)

Interrelationship between hepatic lipase expression, proinflammatory cytokines, and HDL metabolism

TYPE 2007
Renewal
$86,360

Yao, Zemin (University of Ottawa)

Analysis of non-truncation apoB mutations associated with human familial hypobetalipoproteinemia

TYPE 2007
Renewal
$82,538

Yarmo, Michelle (University of Ottawa)

Macrophage-adipose cell interactions in obesity and cardiovascular disease

TYPE 2007
Master's Studentship
(Pending)
$18,000

Zandstra, Peter W. (University of Toronto)

Controlling bioreactor condition to optimize regenerative potential of cardiomyocytes

TYPE 2007
New Annual
$89,725

Zhang, Xia (University of Ottawa)

Poststroke treatment with cannabinoids for promoting neuronal regeneration

TYPE 2007
New Annual
$59,670

Zhang, Zhu-Xu (London Health Sciences Centre)

Therapeutic potential and mechanism of double-negative regulatory T (DN-Treg) cells mediated tolerance in heart transplantation

TYPE 2007
New Annual
$78,294

Zimmerman, Deborah L. (Ottawa Health Research Institute)

Control of hypertension in end stage renal disease, a randomized cross-over study comparing daily hemofiltration to conventional hemodialysis

TYPE 2007
New Annual
(Pending)
$53,327
Last Updated ( Monday, 04 February 2008 )