HSFC Personnel Awards Program - 2007/2008

Personnel awards offered by HSFC for 2007/2008:

Visiting Scientists

  • Leyva, Delfin R. (Research Centre, Holguin University Hopsital)
    Sponsor: Pierce, Grant N. (Stroke and Vascular Disease, St. Boniface Hospital Research Centre)
    Effect of dietary flaxseed on symptoms of cardiovascular disease in patients with peripheral arterial disease. 

  • Rodger, Marc A. (Hematology, Ottawa Health Research Institute)
    Sponsor: Greer, Ian Andrew (Hull York Medical School, University of York)
    Thrombophilia and placenta mediated pregnancy complications: establishing causality and developing preventative strategies. 

New Investigator

  • Butcher, Ken S. (Medicine, University of Alberta)
    Cerebral perfusion and blood pressure in intracerebral hemorrhage: a safety study.
  • Gros, Robert (Vascular Biology Research Group, Robarts Research Institute)
    Regulators of G-protein-coupled receptor-mediated vascular responses.
  • Lear, Scott A. (Kinesiology, Simon Fraser University)
    Multicultural community health assessment trial (M-CHAT): a longitudinal study of body fat distribution and cardiovascular risk in four ethnic populations.
  • Sawicki, Grzegorz (Pharmacology, University of Saskatchewan)
    Chemical modifications of myosin light chain 1 in oxidative stress and its degradation by MMP-2.
  • Seubert, John M. (Pharmacy & Pharmaceutical Sciences, University of Alberta)
    Role of eicosanoids in the heart: implications of arachidonic acid and its metabolites in regulating myocardial function and ischemic injury.
  • Shearer, Jane (Biochemistry & Molecular Sciences, University of Calgary)
    Mechanisms of glycogen-induced insulin resistance in diabetic cardiomyopathy.

Research Fellowship

  • An, Ding (Joslin Diabetes Center, Harvard Medical Center)
    The role of TRB3 in insulin signaling and glucose transport in skeletal muscle.
    Supervisor: Goodyear, Laurie J. 
  • Chakrabarti, Subhadeep (Physiology, University of Alberta)
    AMPK and PPAR activators on AGE-mediated endothelial dysfunction.
    Supervisor: Davidge, Sandra T. 
  • Chan, Matthew W. C. (CIHR Group in Matrix Dynamics, University of Toronto)
    Regulation of myofibroblast differentiation by mechanical loading.
    Supervisor: McCulloch, Christopher A. G. 
  • Esfandiarei, Mitra (Pharmacology, University of British Columbia)
    The role of integrin-linked kinase in modulation of vascular smooth muscle migration and atherosclerotic intimal thickening in type II diabetes.
    Supervisor: van Breemen, Cornelis 
  • Ghanem, Noel (Neuroscience Research Group, University of Ottawa)
    Neural precursor cell mediated regeneration in the brain following stroke.
    Supervisor: Slack, Ruth S. 
  • Ghayur, Muhammad Nabeel (Medicine, McMaster University)
    Confocal microscopy of intact living glomeruli and resistance arterioles: a potentially novel insight into renal Ca2+ physiology.
    Supervisor: Janssen, Luke J. 
  • Hodge, Rebecca D. (Pathology, University of Washington)
    Capacity of Tbr2-positive progenitors to promote regeneration in the injured adult brain.
    Supervisor: Hevner, Robert F. 
  • Kuk, Jennifer L. (Medicine, McMaster University)
    Influence of ethnicity and therapeutic intervention on tissue functionality and metabolic risk.
    Supervisor: Sharma, Arya M. 
  • Landry, Josette-Renee (Chromatin and Genomic Expression, IRCM)
    Transcriptional regulatory network of Elf- 1 in vascular endothelium development and angiogenesis.
    Supervisor: Robert, François 
  • Lemarie, Catherine A. (Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital)
    AT1 receptors are essential in aldosterone signaling in VSMC and impairment of EPCs differentiation.

    Supervisor: Schiffrin, Ernesto L. 
  • Li, Hongliang (Richard Lewar Center of Excellence, Toronto General Research Institute)
    Roles of A20 signaling on heart failure mediated by myocarditis & cardiac hypertrophy.
    Supervisor: Liu, Peter P. 
  • Loewen, Matthew Eric (Anesthesiology, Pharmacology & Therapeutics, University of British Columbia)
    Dynein and Kinesin motor regulation of surface expression of cardiac Kv channels.
    Supervisor: Fedida, David 
  • Lorenzen-Schmidt, Ilka (Physiology and Medicine, University of Toronto)
    Regulation of cAMP and contractility by Pi3Kgamma, phosphodiesterases (PDEs) and beta- AR signaling.
    Supervisor: Backx, Peter H. 
  • Magalhaes, Ana Cristina R. (Cell Biology, Robarts Research Institute)
    Intracellular trafficking of mGluR5: role of rab proteins in the regulation of this receptor activity.
    Supervisor: Ferguson, Stephen S. G. 
  • McGowan, Cheri L. (Cardiology, University of Toronto)A
    Cholesterol - independent effects of HMG- CoA reductase inhibitor therapy on neural control of the heart and circulation in heart failure.
    Supervisor: Floras, John S. 
  • Mente, Andrew (Cardiology, McMaster University)
    Nutrigenomics and cardiovascular disease.
    Supervisor: Anand, Sonia S. 
  • Nader, Moni (Cellular and Molecular Medicine, University of Ottawa)
    Potential role of SLMAP in regulating the excitation- contraction apparatus during heart remodeling.
    Supervisor: Tuana, Balwant S. 
  • Ouzounian, Maral (Cardiology, University of Toronto)
    Biomarkers to distinguish diastolic from systolic heart failure: towards personalized medicine.
    Supervisor: Liu, Peter P. 
  • Paravicini, Tamara M. (Kidney Research Centre, Ottawa Health Research Institute)
    TRPM7 signaling in hypertension.
    Supervisor: Touyz, Rhian M. 
  • Qi, Dake (Internal Medicine, Yale University)
    Macrophage migration inhibitory factor (MIF) in the ischemic heart.
    Supervisor: Young, Lawrence H. 
  • Ribeiro, Fabiola M. (Physiology and Pharmacology, Robarts Research Institute)
    Effect of optineurin and GRK2 knockdown on metabotropic glutamate receptor signalling and excitotoxic cell death.
    Supervisor: Ferguson, Stephen S. G. 
  • Rousselet, Estelle (Biochemical Neuroendocrinology, IRCM)
    Role of PCSK9 in mice model of ischemic stroke.
    Supervisor: Seidah, Nabil G. 
  • Scozzafava, Giuseppe James (Medicine, University of Alberta)
    Cerebral perfusion and blood pressure in intracerebral hemorrhage: a safety study.
    Supervisor: Butcher, Ken S. 
  • Xu, Guoxiong (Molecular Structure and Function Program, Hospital for Sick Children)
    Studying the role of BMP- 9 in vascular homeostasis through disease models.
    Supervisor: Letarte, Michelle V. 
  • Westendorp, Bart (Cellular and Molecular Medicine, University of Ottawa)
    E2F6: essential regulator of cardiac growth?
    Supervisor: Tuana, Balwant S.

Doctoral Research Award

  • Arguin, Guillaume (Pharmacologie, Université de Sherbrooke)
    Mecanisme de regulation du recepteur de l' inositol 1,4,5- trisphosphate de type 2 (IP3R-2).
    Supervisor: Guillemette, Gaètan 
  • Artemenko, Yulia (Growth and Development, Ottawa Health Research Institute)
    Role of SHIP2 in adipose tissue growth.
    Supervisor: Sorisky, Alexander 
  • Aubin, Marie-Claude (Pharmacologie, Université de Montréal)
    Obesity and intrinsic cardiac remodeling following an ischemic insult.
    Supervisor: Perrault, Louis P.
  • Bai, Ni (Nicola) (Anesthesiology, St. Paul's Hospital)
    Mechanisms underlying particulate matter air pollution-induced atherosclerosis.
    Supervisor: van Eeden, Stephan F. 
  • Beyea, Michael M. (Biochemistry, Robarts Research Institute)
    Attenuating foam cell formation, smooth muscle cell proliferation and atherosclerosis using 24 (s), 25-epoxycholesterol.
    Supervisor: Huff, Murray W. 
  • Dupasquier, Chantal (Physiology, University of Manitoba)
    The effects of trans fatty acid supplementation on inflammation, obesity, and atherosclerosis.
    Supervisor: Pierce, Grant N. 
  • Hammoud, Lamis (Physiology and Pharmacology, University of Western Ontario)
    Role of TIMP-3 in heart failure and postnatal cardiomyocyte proliferation.
    Supervisor: Feng, Qingping 
  • David, Laurence S. (Neuroscience, University of British Columbia)
    Cardiac 1H T-type calcium channels and hypertension.
    Supervisor: Snutch, Terrance P. 
  • Hines, Dustin J. (Psychiatry, University of British Columbia)
    Microlagia cells limit the spread of neurotrauma in a model of stroke.
    Supervisor: MacVicar, Brian A. 
  • Iremonger, Karl J. (Physiology and Biophysics, University of Calgary)
    Delayed glutamate release allows central neurons to function as efficient integrators of synaptic inputs.
    Supervisor: Bains, Jaideep S. 
  • Kodiha, Mohamed (Physiology, McGill University)
    Signaling through PI3 kinase controls nuclear transport in stressed cells.
    Supervisor: Stochaj, Ursula 
  • Kwok, Trevor (Molecular and Medical Genetics, University of Toronto)
    Identifying and characterizing loci that confer resistance to a calcium channel blocker.
    Supervisor: Roy, Peter J. 
  • Lam, Hung D. (Physiology, McGill University)
    Mechanism of HERG gating: a structure- function study.
    Supervisor: Shrier, Alvin 
  • Leduc, Martin (Pediatrics, Opthalmology & Pharmacology, Hôpital Sainte-Justine)
    Dimerization of prostaglandin E2 receptors.
    Supervisor: Chemtob, Sylvain 
  • Mattar, Pierre A. (Biochemistry & Molecular Biology, University of Calgary)
    Enhancing neurogenesis for stroke repair using neurogenin 2.
    Supervisor: Schuurmans, Carol J. 
  • Mraiche, Fatima (Biochemistry, University of Alberta)
    The role of the Na+ / H+ exchanger in cardiac hypertrophy.
    Supervisor: Fliegel, Larry 
  • Sankaralingam, Sowndramalingam (Physiology, University of Alberta)
    The roles of arginase and LOX-1 in the pathophysiology of preeclampsia.
    Supervisor: Davidge, Sandra T. 
  • Singh, Ranji (Paediatrics, University of British Columbia)
    Hyperhomocysteinemia and epigenetic regulation of hepatic lipid metabolism.
    Supervisor: Devlin, Angela M. 
  • Smith, Pauline M. (Physiology, Queen's University)
    Adiponectin acts at the area postrema to influence cardiovascular control.
    Supervisor: Ferguson, Alastair V. 
  • Tai, Chao (Psychiatry, University of British Columbia)
    R-type VGCC's and TRP channels contribute to stroke-induced neuronal death.
    Supervisor: MacVicar, Brian A. 
  • Vaid, Moninder (Pharmacology & Therapeutics, University of British Columbia)
    Effects of cardiac ischemia on channel kinetics using real-time voltage clamp fluorimetry.
    Supervisor: Fedida, David 
  • Yacoub, Daniel (Pathologie expérimentale, Institut de cardiologie de Montréal)
    Implication de la P-sélectine dans l'athéro-thrombase.
    Supervisor: Merhi, Yahye 
  • Zhou, Ning (Psychiatry, University of British Columbia)
    Signaling pathways underlying spreading depression and ischemic depolarization.
    Supervisor: MacVicar, Brian A.

Nursing Research Fellowship

  • Houle, Julie (Faculté de pharmacie, Université Laval)
    Programme d'Activité physique en Réadaptation cardiaque Adapté et Dirigé par une Infirmière clinicienne Spécialisée (projet PARADIS).
    Supervisor: Poirier, Paul 
  • Seneviratne, Cydnee C. (Faculty of Nursing, University of Calgary)
    Interprofessional practices in cardiac rehabilitation.
    Supervisor: King, Kathryn M. ; Mather, Charles M.