Dr. Yuichiro Maekawa
Toronto General Hospital
Biochemical molecules known as cytokines send critical information between the many different cells of the immune system, helping the body protect itself from disease. Dr. Yuichiro Maekawa is examining one of the most significant of these molecules, called interleukin-1 (IL-1), which appears to play a key role in the inflammation that can cause heart failure following a heart attack.
This molecule is one of the leading mediators in the immune response, initiating measures such as inflammation to defend the body from disease. High levels of this molecule - which seem closely related to a poorer prognosis - have been measured in patients suffering from heart failure.
Working as a postdoctoral fellow at the Heart&Stroke/Richard Lewar Centre of Excellence in Cardiovascular Research, part of Toronto’s University Health Network, Dr. Maekawa will study the various components of the molecule and the specific function each has in the inflammatory process.
The Heart and Stroke Foundation congratulates Dr. Maekawa on this promising research, which is supervised by Dr. Peter Liu.
Supported by AstraZeneca Canada Inc.