Dr. Michael Czubryt
University of Manitoba
Dr. Michael Czubryt’s research is trying to determine why some people develop heart disease while others do not. He is interested in how genes are turned ‘on’ or ‘off,’ a process known as gene expression. He is particularly interested in gene expression in cardiac muscle cells (found in the heart) and smooth muscle cells (found in blood vessel walls). The pattern of gene expression changes during the development of conditions such as congestive heart failure. Dr. Czubryt’s research team studies how and why these patterns and pathways change.
His current study investigates the reasons why heart failure can occur differently in men and women. He will look at the role that estrogen may play in controlling gene expression in heart failure. He will also investigate genes that control the thickening of heart muscle in order to understand how they are turned ‘on’ or ‘off.’ Thickened heart muscle can lead to congestive heart failure.
Dr. Czubryt is an Assistant Professor of Physiology in the Division of Stroke and Vascular Disease at the University of Manitoba. He has a doctorate degree in physiology. He achieved this year’s highest rating in the Heart and Stroke Foundation of Canada’s New Investigator Award competition.