Heart and Stroke Foundation of Canada Research Programs - 2007 HSFO Grants-in-Aid and Career Investigator Competition Results

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Heart and Stroke Foundation of Ontario

Results of September 2006 Grant-in-Aid and Career Investigator Competitions

The Heart and Stroke Foundation of Ontario is pleased to announce the scientists from Ontario who were awarded Grant-in-Aid / Career Investigator funding in the September 2006 competition.

The results posted below are to be considered preliminary only. An official letter will be sent to all applicants the week of March 19, 2007, along with the budget / funding details and rankings. Career Investigator awards do not have first year amounts, however the standard stipend applies.

For those awards identified as "pending", funding is encumbered until additional information is provided. Applicants will be contacted in the near future in this regard. Some proposals were not ranked highly enough to receive full funding. In such cases, the Foundation has provided a terminal award, in order to assist scientists in maintaining some level of research activity until a re-application can be made.

The Foundation requests that applicants do not write or telephone with any enquiries before receiving the award letters.

Adeli, Khosrow (Hospital for Sick Children) Molecular mechanisms of hepatic VLDL overproduction in insulin resistance	TYPE	5 Year
	Renewal	$115,917
Alhesayen, Abdurrahman, O (St. Michael's Hospital) Exploring the role of cGMP in human heart failure	TYPE	3 Year
	New Annual(pending)	$75,452
Athale, Uma H. (McMaster University) Evaluation for inherited and acquired prothrombotic defects predisposing to symptomatic thromboembolism in children with acute lymphoblastic leukemia	TYPE	2 Year
	New Annual(pending)	$45,351
Austin, Richard C. (McMaster University) Role of the sterol regulatory element-binding proteins in foam cell formation and atherogenesis	TYPE	3 Year
	New Annual	$93,837
Austin, Richard C. (McMaster University) Inhibition of tissue factor procoagulant activity by GRP78 and its role in thrombosis	TYPE	3 Year
	Renewal	$84,991
Belik, Jaques (Hospital for Sick Children) ENOS uncoupling and role of bone morphogenetic protein-9 in the regulation of pulmonary vascular tone during development and following pulmonary hypertension	TYPE	2 Year
	New Annual(pending)	$86,906
Bendeck, Michelle P. (University of Toronto) Discoidin domain receptors (DDR1) in atherosclerosis	TYPE	2 Year
	New Annual	$84,860
Bolz, Steffen-Sebastian (University of Toronto) Mechanisms that regulate the pressure-dependent activation of the sphingosine-1-phosphate signalling pathway in resistance arteries	TYPE	2 Year
	New Annual(pending)	$70,190
Boughner, Derek R. (University of Western Ontario) Aortic sclerosis in an animal model: progression, regression and evaluation	TYPE	1 Year
	Renewal	$69,918
Cepinskas, Gediminas (Lawson Health Research Institute) Cerebrovascular endothelial cell dysfunction in sepsis: role of astrocytes	TYPE	2 Year
	New Annual	$81,883
Chan, Anthony K.C. (McMaster University) Surface mechanisms of anticoagulant ATH complex	TYPE	4 Year
	Renewal	$84,450
Chauhan, Vijay S. (University Health Network) Characterizing ventricular repolarization alternans in human cardiomyopathy	TYPE	3 Year
	Renewal(pending)	$84,004
Cheung, Angela M. (University Health Network) The role of vitamin K in aortic calcification in postmenopausal women: an exploratory analysis	TYPE	1 Year
	New Annual(pending)	$60,166
Cote, Graham P. (Queen's University) Formation and function of invadopodia in vascular smooth muscle cells	TYPE	5 Year
	Renewal	$88,919
Crowther, Mark A. (McMaster University) Evaluating the incidence and clinical importance of heparin induced thrombocytopenia in the critically ill	TYPE	3 Year
	New Annual(pending)	$28,172
Cybulsky, Myron I. (University Health Network) Initiation of atherosclerosis: mechanisms and cell biology	TYPE	5 Year
	Career Investigator
Cybulsky, Myron I. (University Health Network) Monocyte recruitment in atherosclerosis	TYPE	3 Year
	Renewal	$115,560
Cybulsky, Myron I. (University Health Network) Regional differences in the arterial intima that predispose the artery wall to atherogenesis	TYPE	2 Year
	Renewal(pending)	$102,606
Drangova, Maria (Robarts Research Institute) Cardiac imaging for therapy guidance and pre-clinical research studies	TYPE	5 Year
	Career Investigator
Dumont, Daniel J. (Sunnybrook Health Sciences Centre) Molecular studies examining the role of lymphangiogenic signalling in heart disease	TYPE	3 Year
	Renewal(pending)	$84,900
Epand, Richard M. (McMaster University) Development of potent antiatherogenic peptides	TYPE	3 Year
	New Annual	$79,250
Feldman, Ross D. (Robarts Research Institute) Determinants of adenylyl cyclase mediated vascular responses	TYPE	2 Year
	New Annual	$109,499
Feldman, Ross D. (Robarts Research Institute) Acute vascular effects of aldosterone	TYPE	2 Year
	New Annual	$76,550
Feng, Qingping (Lawson Health Research Institute) Cardioprotection by erythropoietin: role of nitric oxide	TYPE	5 Year
	Renewal(pending)	$119,732
Ferguson, Alastair (Queen's University) Adiponectin actions in autonomic control centres of the brain	TYPE	5 Year
	Renewal(pending)	$118,707
Finestone, Hillel M. (Ottawa Health Research Institute) Driving post-stroke: a prospective study of community integration and driving habits	TYPE	1 Year
	Renewal(pending)	$39,279
Gaisano, Herbert Y. (University of Toronto) SNARE regulation of cardiac sulfonylurea receptor. a novel drug target for cardiac ischemia	TYPE	4 Year
	Renewal(pending)	$99,717
Gao, Yu-Jing (McMaster University) Perivascular adipose tissue, reactive oxygen species and hypertension	TYPE	2 Year
	New Annual(pending)	$73,000
Gilbert, Richard E. (St. Michael's Hospital) Pathogenetic role of protein kinase c-beta in diabetic cardiomyopathy: interventional and translational studies	TYPE	2 Year
	New Annual(pending)	$87,591
Ginsberg, Jeffrey S. (McMaster University) Diagnosis and management of thromboembolic disorders in multiple patient populations	TYPE	3 Year
	Career Investigator
Gorczynski, Reginald M. (University Health Network) Regulation of transplant rejection and inflammation in CD200tg and CD200R KO mice	TYPE	3 Year
	New Annual	$90,400
Gotlieb, Avrum I. (University Health Network) Cell biology of heart valve interstitial cells	TYPE	2 Year
	New Annual	$88,780
Graham, Charles H. (Queen's University) Mechanisms regulating the development and pathophysiology of pre-eclamptic hypertension	TYPE	3 Year
	Renewal	$94,943
Gros, Robert (Robarts Research Institute) Regulators of G-protein-coupled receptor-mediated vascular responses	TYPE	2 Year
	New Annual(pending)	$71,295
Gross, Gil J. (Hospital for Sick Children) Ventricular repolarization in bradycardic electrical remodeling	TYPE	3 Year
	Renewal(pending)	$86,914
Gross, Peter L. (St. Michael's Hospital) Defining how atorvastatin inhibits platelets	TYPE	2 Year
	New Annual	$71,266
Grover, Ashok K. (McMaster University) Effects of reactive oxygen on Na-Ca exchange in coronary artery	TYPE	3 Year
	Renewal(pending)	$102,017
Gupta, Radhey S. (McMaster University) Studies on mammalian adenosine kinase and its inhibitors	TYPE	3 Year
	Renewal(pending)	$87,602
Haas, Tara L. (York University) The regulation of angiogenic factors by shear stress	TYPE	2 Year
	New Annual(pending)	$79,750
Hache, Robert J.G. (Ottawa Health Research Institute) Regulation of preadipocyte differentiation by glucocorticoids in model systems	TYPE	3 Year
	New Annual	$77,014
Harper, Mary-Ellen (University of Ottawa) Novel AMPK-gamma mutations in humans: implications for skeletal muscle energy metabolism	TYPE	3 Year
	New Annual(pending)	$93,725
Hegele, Robert A. (Robarts Research Institute) Genomics of hypertriglyceridemia	TYPE	2 Year
	New Annual(pending)	$108,208
Hegele, Robert A. (Robarts Research Institute) Phenomics and genomics of atherosclerosis in monogenic metabolic syndrome	TYPE	5 Year
	Renewal	$109,999
Huff, Murray W. (Robarts Research Institute) Regulation of hepatic lipoprotein secretion and glucose homeostasis by the citrus flavonoid nobiletin: relationship to atherosclerosis	TYPE	2 Year
	New Annual(pending)	$91,794
Jankov, Robert P. (Sunnybrook Health Sciences Centre) Rho-kinase inhibitors as therapy for chronic neonatal pulmonary hypertension	TYPE	2 Year
	New Annual	$80,750
Karmazyn, Morris (University of Western Ontario) Role of adenosine in myocardial hypertrophy and heart failure	TYPE	3 Year
	New Annual(pending)	$93,833
Kawaja, Michael David (Queen's University) Evaluating phenotypic changes in cerebral vessels of stroke-prone spontaneously hypertensive rats: a pilot proteomic investigation	TYPE	2 Year
	New Annual(pending)	$66,762
Langille, B. Lowell (University Health Network) Arterial responses to hemodynamic stresses	TYPE	3 Year
	Renewal(pending)	$89,518
Langille, B. Lowell (University Health Network) Cadherins and regulation of smooth muscle cell function	TYPE	5 Year
	Renewal(pending)	$105,053
Levin, Mindy F. (University of Ottawa) Optimizing arm motor recovery in stroke	TYPE	3 Year
	New Annual(pending)	$41,762
Li, Ren-Ke (University Health Network) Matrix modulation is required to restore cardiac function after cell therapy	TYPE	2 Year
	Renewal(pending)	$91,243
Marcel, Yves L. (University of Ottawa Heart Institute) Macrophage lipid transporters and in vivo reverse cholesterol transport	TYPE	2 Year
	New Annual(pending)	$88,500
Maurice, Donald H. (Queen's University) cAMP-signaling complexes in human vascular endothelial cells: studies on the impact of their numbers, composition and subcellular distribution on cAMP-regulated cellular functions.	TYPE	2 Year
	New Annual(pending)	$83,005
McCulloch, Christopher A. (University of Toronto) Regulation of myofibroblast differentiation by mechanical loading	TYPE	3 Year
	Renewal	$97,021
McPherson, Ruth (University of Ottawa Heart Institute) Genetic determinants of HDL-C	TYPE	3 Year
	New Annual(pending)	$133,182
Medin, Jeffrey A. (University Health Network) Enhancement of gene transfer outcomes for Fabry disease	TYPE	3 Year
	New Annual(pending)	$125,247
Melo, Luis Gabriel (Queen's University) Cell-based gene therapy strategy to enhance neovascularization and healing of infarcted myocardium	TYPE	2 Year
	Renewal(pending)	$97,228
Miller, Judith A. (University Health Network) Glomerular hemodynamic modulation in type 1 diabetes mellitus	TYPE	2 Year
	New Annual(pending)	$62,614
Milne, Ross W. (University of Ottawa Heart Institute) Advanced glycation end products and diabetic atherosclerosis	TYPE	3 Year
	Renewal(pending)	$71,677
Morris, Catherine E. (Ottawa Health Research Institute) The mechanosensitivity of pacemaker channels	TYPE	3 Year
	New Annual(pending)	$80,914
Nag, Sukriti (University Health Network) Regulation of cerebrovascular homeostasis and repair by angiogenic factors	TYPE	2 Year
	Renewal(pending)	$87,839
O'Donnell, Martin J. (McMaster University) INTERSTROKE; Importance of conventional and emerging risk factors for stroke in different regions of the world and in different ethnic groups: A pilot case-control study.	TYPE	3 Year
	New Annual(pending)	$105,750
Ofosu, Frederick A. (McMaster University) Platelet-derived serine proteases and platelet activation	TYPE	2 Year
	Renewal(pending)	$70,398
Opas, Michal J. (University of Toronto) Calreticulin: cell and developmental biology	TYPE	3 Year
	Renewal(pending)	$110,150
Opavsky, Mary Anne (Hospital for Sick Children) Heart failure and the coxsackie-adenovirus receptor (CAR): insights through a novel heart targeted CAR transgenic mouse.	TYPE	3 Year
	Renewal(pending)	$92,080
Pang, Stephen C. (Queen's University) Hypoxia inducible expression of atrial natriuretic peptide: a potential preemptive therapy for myocardial infarction	TYPE	3 Year
	Renewal(pending)	$85,014
Parker, John D. (Mount Sinai Hospital) Clinical studies concerning nitrate pharmacology and autonomic physiology in congestive heart failure	TYPE	5 Year
	Career Investigator
Parkinson, John (Hospital for Sick Children) A combined theoretical/experimental approach to understanding sequence-structure-function relationships in elastin	TYPE	2 Year
	Renewal	$57,400
Radisic, Milica (University of Toronto) Peptide modified photocrosslinkable chitosan for cell therapy in myocardial infarction	TYPE	3 Year
	New Annual(pending)	$50,974
Rand, Margaret L. (Hospital for Sick Children) The procoagulant surface of activated platelets: persistence in vitro and in vivo	TYPE	3 Year
	Renewal(pending)	$85,803
Reid, Robert D. (University of Ottawa Heart Institute) A program to reduce cardiovascular risk among family members of patients with coronary heart disease	TYPE	3 Year
	New Annual(pending)	$100,343
Reid, Robert D. (University of Ottawa Heart Institute) Efficacy and cost-effectiveness of behavioural counselling for exercise behaviour in men and women following AMI and PCI	TYPE	2 Year
	Renewal(pending)	$74,641
Roberts, Robert (University of Ottawa Heart Institute) Genome-wide scan to identify coronary artery disease genes	TYPE	3 Year
	New Annual(pending)	$118,612
Robinson, Lisa A. (Hospital for Sick Children) Regulation of the membrane-anchored chemokine, fractalkine, by thromboxane A2	TYPE	3 Year
	Renewal	$88,868
Rochon, Elizabeth A (University of Toronto) Understanding the behavioural, neural and communicative changes underlying the treatment for anomia in aphasia	TYPE	2 Year
	Renewal(pending)	$89,170
Rodger, Marc A. (Ottawa Health Research Institute) Thrombophilia and placenta mediated pregnancy complications	TYPE	5 Year
	Career Investigator
Roy, Eric A. (University of Waterloo) Neuropsychological profiles and neuroanatomic correlates of limb apraxia	TYPE	5 Year
	Renewal(pending)	$69,864
Rush, James W.E. (University of Waterloo) Vascular endothelium adaptations to hypertension and exercise	TYPE	2 Year
	Renewal	$72,383
Sandig, Martin (University of Western Ontario) Integrin signaling in monocyte transendothelial migration	TYPE	2 Year
	New Annual(pending)	$82,797
Simmons, Craig A. (University of Toronto) The role of extracellular matrix biomechanics in aortic valve sclerosis	TYPE	3 Year
	New Annual(pending)	$81,125
Siu, Samuel C. (University Health Network) Neurodevelopmental outcomes in offsprings of women with heart disease	TYPE	2 Year
	Renewal(pending)	$40,070
Slack, Ruth (Ottawa Health Research Institute) Mitochondrial dynamics in neuronal injury	TYPE	3 Year
	New Annual	$88,247
Smith, Steven P. (Queen's University) Lipoprotein(a) in atherosclerosis: assembly and interaction with extracellular matrix proteins	TYPE	3 Year
	Renewal	$87,856
Sorisky, Alexander (Ottawa Health Research Institute) Pro-atherogenic responses of human adipocytes to TSH	TYPE	3 Year
	Renewal	$91,215
Spencer, Frederick A. (McMaster University) Clinical epidemiology and management of cardiovascular and venous thromboembolic disease	TYPE	5 Year
	Career Investigator
Stewart, Duncan J. (St. Michael's Hospital) Role of angiopoietins in regulation of angiogenesis	TYPE	2 Year
	New Annual(pending)	$67,734
Suskin, Neville (Lawson Health Research Institute) Comprehensive cardiac rehabilitation programming for patients following transient ischemic attack	TYPE	2 Year
	New Annual(pending)	$126,586
Suuronen, Erik J. (University of Ottawa Heart Institute) Recruitment of endogenous circulating progenitor cells for cardiac regeneration using acellular tissue-engin biomatrices	TYPE	2 Year
	New Annual	$89,098
Sweeney, Gary (York University) Direct effects of adiponectin on cardiomyocytes	TYPE	3 Year
	Renewal(pending)	$73,500
Vaillancourt, Christian (Ottawa Health Research Institute) Effectiveness of dispatch-assisted CPR instructions: an evaluation of 9-1-1 calls	TYPE	3 Year
	New Annual(pending)	$117,109
Van Arsdell, Glen S. (Hospital for Sick Children) The influence of postoperative systemic oxygen transport on neurologic outcomes in infants undergoing the No	TYPE	2 Year
	New Annual	$59,000
Verma, Subodh (St. Michael's Hospital) ACE2: Novel regulator of endothelial function and atherosclerosis	TYPE	3 Year
	New Annual(pending)	$104,058
Waddell, Thomas K (University Health Network) The role of galectin-3 in xenograft rejection	TYPE	3 Year
	New Annual	$89,539
Wang, Hui Di (Brock University) Reactive oxygen species mediates angiotensin II induced ET-1 release from vascular adventitial fibroblasts	TYPE	2 Year
	New Annual(pending)	$56,500
Warkentin, Theodore E. (McMaster University) Heparin-induced thrombocytopenia	TYPE	3 Year
	Renewal(pending)	$99,894
Weisel, Richard D. (University Health Network) Cardiac regeneration: improving the response to injury	TYPE	3 Year
	Renewal(pending)	$73,602
Wen, Xiao-Yan (University Health Network) Investigation of lysophospatidic acid (LPA) generation and platelet function in newly developed lpdlr phospholipase deficient mice	TYPE	2 Year
	New Annual	$91,209
Werstuck, Geoffrey H. (McMaster University) Investigating the role of glycogen synthase kinase (GSK)-3 in atherogenesis	TYPE	3 Year
	Renewal(pending)	$82,914
Wijeysundera, Duminda N. (University Health Network) The EPIC (evaluating perioperative ischemia reduction by clonidine) study: a randomized, triple-blinded, placebo-controlled trial of combining clonidine with chronic beta-blockade in intermediate-to- high risk non-cardiac surgery	TYPE	2 Year
	New Annual(pending)	$92,443
Yang, Kaiping (University of Western Ontario) Early-life origins of visceral adiposity	TYPE	2 Year
	New Annual(pending)	$81,921
Yao, Zemin (University of Ottawa Heart Institute) Interrelationship between hepatic lipase expression, proinflammatory cytokines, and HDL metabolism	TYPE	3 Year
	Renewal(pending)	$84,679
Yao, Zemin (University of Ottawa) Analysis of non-truncation apoB mutations associated with human familial hypobetalipoproteinemia	TYPE	3 Year
	Renewal(pending)	$80,920
Zandstra, Peter W. (University of Toronto) Controlling bioreactor condition to optimize regenerative potential of cardiomyocytes	TYPE	2 Year
	New Annual(pending)	$87,850
Zhang, Zhu-Xu (Lawson Health Research Institute) Therapeutic potential and mechanism of double-negative regulatory T (DN-Treg) cells mediated tolerance in heart transplantation	TYPE	2 Year
	New Annual(pending)	$78,294
Zimmerman, Deborah L. (Ottawa Health Research Institute) Control of hypertension in end stage renal disease, a randomized cross-over study comparing daily hemofiltration to conventional hemodialysis	TYPE	2 Year
	New Annual(pending)	$56,325

Last Updated ( Monday, 07 May 2007 )